J R Sachs
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Explore the profile of J R Sachs including associated specialties, affiliations and a list of published articles.
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52
Citations
607
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Recent Articles
1.
Bunch P, Pavlina A, Lipford M, Sachs J
AJNR Am J Neuroradiol
. 2021 Sep;
42(11):2001-2008.
PMID: 34475194
Background And Purpose: In parathyroid CT, a noncontrast phase aids discrimination of parathyroid lesions (not iodine-containing) from thyroid tissue (iodine-containing). When thyroid iodine is pathologically diminished, this differentiation is difficult...
2.
Erickson J, Benayoun M, Lack C, Sachs J, Bunch P
AJNR Am J Neuroradiol
. 2021 Jun;
42(9):1671-1675.
PMID: 34117021
Background And Purpose: Transient loss of consciousness is commonly evaluated in the emergency department. Although typically caused by epileptic seizure, syncope, or psychogenic nonepileptic seizure, the underlying etiology is frequently...
3.
Bunch P, Hughes R, White E, Sachs J, Frizzell B, Lack C
AJNR Am J Neuroradiol
. 2021 Mar;
42(5):938-944.
PMID: 33664114
Background And Purpose: Among patients undergoing serial neck CTs, we have observed variability in the appearance of the pharyngolaryngeal venous plexus, which comprises the postcricoid and posterior pharyngeal venous plexuses....
4.
Bunch P, Zapadka M, Lack C, Kiell E, Kirse D, Sachs J
AJNR Am J Neuroradiol
. 2020 Aug;
41(9):1712-1717.
PMID: 32763898
Background And Purpose: Internal auditory canal diverticula are focal lucencies along the anterior-inferior aspect of the internal auditory canal fundus. Studies in adults report conflicting data on the etiology and...
5.
Elassaiss-Schaap J, Rossenu S, Lindauer A, Kang S, de Greef R, Sachs J, et al.
CPT Pharmacometrics Syst Pharmacol
. 2016 Nov;
6(1):21-28.
PMID: 27863143
Evaluation of pharmacokinetic/pharmacodynamic (PK/PD) properties played an important role in the early clinical development of pembrolizumab. Because analysis of data from a traditional 3 + 3 dose-escalation design revealed several...
6.
Alba M, Sheng D, Guan Y, Williams-Herman D, Larson P, Sachs J, et al.
Curr Med Res Opin
. 2009 Aug;
25(10):2507-14.
PMID: 19691426
Objective: In clinical trials, the degree of glucose lowering with sitagliptin has been correlated with the magnitude of dipeptidyl peptidase-4 (DPP-4) inhibition over 24 h. Previous studies evaluating sitagliptin doses...
7.
RICE W, Young H, Martin D, Sachs J, Stokes D
Biophys J
. 2001 Apr;
80(5):2187-97.
PMID: 11325721
Na+,K+-ATPase is a heterodimer of alpha and beta subunits and a member of the P-type ATPase family of ion pumps. Here we present an 11-A structure of the heterodimer determined...
8.
Martin D, Sachs J
J Biol Chem
. 2000 Jun;
275(32):24512-7.
PMID: 10831595
The interaction of ligands deemed to be ATP analogues with renal Na(+),K(+)-ATPase suggests that two ATP binding sites coexist on each functional unit. Previous studies in which fluorescein 5-isothiocyanate (FITC)...
9.
Martin D, Marecek J, Scarlata S, Sachs J
Proc Natl Acad Sci U S A
. 2000 Mar;
97(7):3195-200.
PMID: 10706623
The distance that separates alphabeta protomers of the Na(+), K(+)-ATPase in microsomes and in purified membranes prepared from duck nasal salt glands was estimated by measuring fluorescence resonance energy transfer...
10.
Sachs J, Martin D
J Physiol
. 1999 Nov;
520 Pt 3:723-35.
PMID: 10545139
1. K+-Cl- cotransport in human red cell ghosts is inhibited by divalent inorganic cations, soluble polycations and amphipathic organic cations. These findings suggest a common mechanism of inhibition, namely, binding...