J R Friedman
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Explore the profile of J R Friedman including associated specialties, affiliations and a list of published articles.
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21
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1417
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Recent Articles
1.
Drazen J, Dugan B, Friedman J
J Fish Biol
. 2013 Dec;
83(6):1592-612.
PMID: 24298953
Owing to the paucity of data on the red muscle of deep-sea fishes, the goal of this study was to determine the proportions of red muscle in demersal fishes and...
2.
Friedman J, Kaestner K
Cell Mol Life Sci
. 2006 Aug;
63(19-20):2317-28.
PMID: 16909212
The Foxa subfamily of winged helix/forkhead box (Fox) transcription factors has been the subject of genetic and biochemical study for over 15 years. During this time its three members, Foxa1,...
3.
Schultz D, Friedman J, Rauscher 3rd F
Genes Dev
. 2001 Mar;
15(4):428-43.
PMID: 11230151
Macromolecular complexes containing histone deacetylase and ATPase activities regulate chromatin dynamics and are vitally responsible for transcriptional gene silencing in eukaryotes. The mechanisms that target these assemblies to specific loci...
4.
Friedman J, Klein C, Leung J, Woodward H, Ozelius L, Breakefield X, et al.
Neurology
. 2000 Nov;
55(9):1417-8.
PMID: 11087801
No abstract available.
5.
Fredericks W, Ayyanathan K, Herlyn M, Friedman J, Rauscher 3rd F
Mol Cell Biol
. 2000 Jun;
20(14):5019-31.
PMID: 10866659
The t(2;13) chromosomal translocation in alveolar rhabdomyosarcoma tumors (ARMS) creates an oncogenic transcriptional activator by fusion of PAX3 DNA binding motifs to a COOH-terminal activation domain derived from the FKHR...
6.
Peng H, Begg G, Harper S, Friedman J, Speicher D, Rauscher 3rd F
J Biol Chem
. 2000 Apr;
275(24):18000-10.
PMID: 10748030
The Kruppel-associated box (KRAB) domain is a 75-amino acid transcriptional repressor module commonly found in eukaryotic zinc finger proteins. KRAB-mediated gene silencing requires binding to the RING-B box-coiled-coil domain of...
7.
Peng H, Begg G, Schultz D, Friedman J, Jensen D, Speicher D, et al.
J Mol Biol
. 2000 Feb;
295(5):1139-62.
PMID: 10653693
The KRAB domain is a 75 amino acid residue transcriptional repression module commonly found in eukaryotic zinc-finger proteins. KRAB-mediated gene silencing requires binding to the corepressor KAP-1. The KRAB:KAP-1 interaction...
8.
RYAN R, Schultz D, Ayyanathan K, Singh P, Friedman J, Fredericks W, et al.
Mol Cell Biol
. 1999 May;
19(6):4366-78.
PMID: 10330177
Krüppel-associated box (KRAB) domains are present in approximately one-third of all human zinc finger proteins (ZFPs) and are potent transcriptional repression modules. We have previously cloned a corepressor for the...
9.
10.
Friedman J, Fredericks W, Jensen D, Speicher D, Huang X, Neilson E, et al.
Genes Dev
. 1996 Aug;
10(16):2067-78.
PMID: 8769649
The KRAB repression domain is one of the most widely distributed transcriptional effector domains yet identified, but its mechanism of repression is unknown. We have cloned a corepressor, KAP-1, which...