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J P Changeux

Explore the profile of J P Changeux including associated specialties, affiliations and a list of published articles. Areas
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Articles 440
Citations 14363
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Recent Articles
1.
Lou H, Changeux J, Rosenstand A
Neurosci Biobehav Rev . 2016 Apr; 83:765-773. PMID: 27079562
Self-awareness is a pivotal component of conscious experience. It is correlated with a paralimbic network of medial prefrontal/anterior cingulate and medial parietal/posterior cingulate cortical "hubs" and associated regions. Electromagnetic and...
2.
Cohen J, Weber M, Changeux J
Mol Pharmacol . 2015 Mar; 10(6):904-32. PMID: 25771543
Studies are presented of the interaction in a physiological ionic environment of aromatic amine local anesthetics (prilocaine, lidocaine, and dimethisoquin) and Ca++ with receptor-rich membrane fragments isolated from Torpedo electric...
3.
Holton B, Tzartos S, Changeux J
Int J Dev Neurosci . 2014 May; 2(6):549-55. PMID: 24874395
The acetylcholine receptor (AChR) from Torpedo marmorata electric organ exists in a light form (α2βγδ) of apparent molecular weight 250,000. The association of two light forms via an intermolecular δ-δ...
4.
Kasai M, Changeux J
J Membr Biol . 2013 Nov; 7(1):312. PMID: 24177513
No abstract available.
5.
Blumenthal R, Changeux J, Lefever R
J Membr Biol . 2013 Nov; 2(1):351-74. PMID: 24174157
Electrical excitation is interpreted in terms of a cooperative structural transition of membrane protomers coupled with the translocation of a permeant molecule in a non-equilibrium environment. Equations for flow of...
6.
Cartaud J, Benedetti E, Kasai M, Changeux J
J Membr Biol . 2013 Nov; 6(1):81-8. PMID: 24173290
Membrane fragments rich in acetylcholinesterase (AcChE) or in Na(+)-K(+)-ATPase are observed under the electron microscope on thin sections after fixation, after negative staining of unfixed material, and after freeze-etching. Both...
7.
Kasai M, Changeux J
J Membr Biol . 2013 Nov; 6(1):58-80. PMID: 24173289
The reversible binding of(14)C-decamethonium (Deca) to excitable microsacs prepared from the electric tissue ofElectrophorus electricus is followed by an ultracentrifugal assay. α-Bungarotoxin, a snake venom toxin, blocks irreversibly the binding...
8.
Kasai M, Changeux J
J Membr Biol . 2013 Nov; 6(1):24-57. PMID: 24173288
The effect of carbamylcholine (Carb) on the release of(22)Na(+) by excitable microsacs is reversible: Carb does not promote an irreversible lysis of the microsacs. The microsacs form closed vesicles which...
9.
Kasai M, Changeux J
J Membr Biol . 2013 Nov; 6(1):1-23. PMID: 24173287
Excitation of membrane fragments by cholinergic agonists is measuredin vitro by a filtration technique. Membrane fragments which contain high levels of the enzyme acetylcholinesterase and presumably originate from the innervated...
10.
Patrick J, Valeur B, Monnerie L, Changeux J
J Membr Biol . 2013 Nov; 5(1):102-20. PMID: 24172986
The fluorescent dye 1-anilinonapthalene-8-sulfonic acid (ANS) has been used as a probe of changes in membrane conformation accompanying excitation of the electroplax ofElectrophorus electricus. ANS binds reversibly to the excitable...