N Le Novere
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Explore the profile of N Le Novere including associated specialties, affiliations and a list of published articles.
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37
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3083
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Recent Articles
1.
Fucic A, Aghajanyan A, Culig Z, Le Novere N
Pathol Oncol Res
. 2018 Sep;
25(4):1269-1277.
PMID: 30220022
Large investments by pharmaceutical companies in the development of new antineoplastic drugs have not been resulting in adequate advances of new therapies. Despite the introduction of new methods, technologies, translational...
2.
Lloret-Villas A, Varusai T, Juty N, Laibe C, Le Novere N, Hermjakob H, et al.
CPT Pharmacometrics Syst Pharmacol
. 2017 Jan;
6(2):73-86.
PMID: 28063254
Neurodegenerative diseases are a heterogeneous group of disorders that are characterized by the progressive dysfunction and loss of neurons. Here, we distil and discuss the current state of modeling in...
3.
Knight-Schrijver V, Chelliah V, Cucurull-Sanchez L, Le Novere N
Comput Struct Biotechnol J
. 2016 Oct;
14:363-370.
PMID: 27761201
Recent growth in annual new therapeutic entity (NTE) approvals by the U.S. Food and Drug Administration (FDA) suggests a positive trend in current research and development (R&D) output. Prior to...
4.
Swat M, Moodie S, Wimalaratne S, Kristensen N, Lavielle M, Mari A, et al.
CPT Pharmacometrics Syst Pharmacol
. 2015 Jul;
4(6):316-9.
PMID: 26225259
The lack of a common exchange format for mathematical models in pharmacometrics has been a long-standing problem. Such a format has the potential to increase productivity and analysis quality, simplify...
5.
Juty N, Ali R, Glont M, Keating S, Rodriguez N, Swat M, et al.
CPT Pharmacometrics Syst Pharmacol
. 2015 Jul;
4(2):e3.
PMID: 26225232
BioModels is a reference repository hosting mathematical models that describe the dynamic interactions of biological components at various scales. The resource provides access to over 1,200 models described in literature...
6.
Ajmera I, Swat M, Laibe C, Le Novere N, Chelliah V
CPT Pharmacometrics Syst Pharmacol
. 2013 Jul;
2:e54.
PMID: 23842097
Diabetes is a chronic and complex multifactorial disease caused by persistent hyperglycemia and for which underlying pathogenesis is still not completely understood. The mathematical modeling of glucose homeostasis, diabetic condition,...
7.
Adams R, Tsorman N, Stratford K, Akman O, Gilmore S, Juty N, et al.
J Biol Rhythms
. 2012 Aug;
27(4):328-32.
PMID: 22855577
Time-dependent light input is an important feature of computational models of the circadian clock. However, publicly available models encoded in standard representations such as the Systems Biology Markup Language (SBML)...
8.
Wolkenhauer O, Fell D, De Meyts P, Bluthgen N, Herzel H, Le Novere N, et al.
IET Syst Biol
. 2009 May;
3(3):131-6.
PMID: 19449974
The following report selects and summarises some of the conclusions and recommendations generated throughout a series of workshops and discussions that have lead to the publication of the Science Policy...
9.
Le Novere N
Pharmacopsychiatry
. 2008 Oct;
41 Suppl 1:S28-31.
PMID: 18756417
Most neurological diseases are multifactorial diseases, where environmental conditions combine with genetic background or somatic mutations to trigger a pathological state. In the case of Parkinson's Disease and Schizophrenia, recent...
10.
Le Novere N, Li L, Girault J
Cell Mol Life Sci
. 2008 May;
65(14):2125-7.
PMID: 18488140
No abstract available.