J L Galzi
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Explore the profile of J L Galzi including associated specialties, affiliations and a list of published articles.
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35
Citations
1428
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Recent Articles
1.
Palanche T, Ilien B, Zoffmann S, Reck M, Bucher B, Edelstein S, et al.
J Biol Chem
. 2001 Jul;
276(37):34853-61.
PMID: 11459843
G protein-coupled receptors are thought to mediate agonist-evoked signal transduction by interconverting between discrete conformational states endowed with different pharmacological and functional properties. In order to address the question of...
2.
Lukas R, Lucero L, Buisson B, Galzi J, Puchacz E, Fryer J, et al.
Eur J Neurosci
. 2001 Jun;
13(10):1849-60.
PMID: 11403678
Nicotinic acetylcholine receptors (nAChR) composed of chick alpha7 subunits mutated to threonine at amino acid valine-251 in the putative channel-lining M2 domain were expressed heterologously in several neuron-like and non-neuronal...
3.
Valenzuela-Fernandez A, Palanche T, Amara A, Magerus A, Altmeyer R, Delaunay T, et al.
J Biol Chem
. 2001 May;
276(28):26550-8.
PMID: 11352904
The chemokine stromal cell-derived factor 1 (SDF-1) is the natural ligand for CXC chemokine receptor 4 (CXCR4). SDF-1 inhibits infection of CD4+ cells by X4 (CXCR4-dependent) human immunodeficiency virus (HIV)...
4.
Vollmer J, ALIX P, Chollet A, Takeda K, Galzi J
J Biol Chem
. 1999 Dec;
274(53):37915-22.
PMID: 10608858
A functional fluorescent neurokinin NK2 receptor was constructed by joining enhanced green fluorescent protein to the amino-terminal end of the rat NK2 receptor and was expressed in human embryonic kidney...
5.
Corringer P, Bertrand S, Galzi J, Devillers-Thiery A, Changeux J, Bertrand D
Novartis Found Symp
. 1999 Sep;
225:215-24; discussion 224-30.
PMID: 10472058
Nicotinic acetylcholine receptors are homo- or heteropentameric proteins belonging to the superfamily of receptor channels including the glycine and GABA-A receptors. Affinity labelling and mutagenesis experiments indicated that the M2...
6.
Weill C, Galzi J, Chasserot-Golaz S, Goeldner M, Ilien B
J Neurochem
. 1999 Jul;
73(2):791-801.
PMID: 10428077
Four recombinant human M1 (hM1) muscarinic acetylcholine receptors (mAChRs) combining several modifications were designed and overexpressed in HEK293 cells. Three different fluorescent chimera were obtained through fusion of the receptor...
7.
Corringer P, Bertrand S, Galzi J, Devillers-Thiery A, Changeux J, Bertrand D
Neuron
. 1999 May;
22(4):831-43.
PMID: 10230802
In the alpha7 nicotinic acetylcholine receptors, we analyze the contribution of mutations E237A and V251T, together with the proline insertion P236', in the conversion of the charge selectivity from cationic...
8.
Fluorescent muscarinic EGFP-hM1 chimeric receptors: design, ligand binding and functional properties
Weill C, Ilien B, Goeldner M, Galzi J
J Recept Signal Transduct Res
. 1999 Mar;
19(1-4):423-36.
PMID: 10071775
We describe the construction, expression and characterization of recombinant proteins comprising the enhanced green fluorescent protein (EGFP) fused to the amino-terminal part of the muscarinic hM1 receptor together or not...
9.
Krause R, Buisson B, Bertrand S, Corringer P, Galzi J, Changeux J, et al.
Mol Pharmacol
. 1998 Mar;
53(2):283-94.
PMID: 9463487
We report that preapplication of ivermectin, in the micromolar range, strongly enhances the subsequent acetylcholine-evoked current of the neuronal chick or human alpha7 nicotinic acetylcholine receptors reconstituted in Xenopus laevis...
10.
Galzi J, Bertrand S, Corringer P, Changeux J, Bertrand D
EMBO J
. 1996 Nov;
15(21):5824-32.
PMID: 8918460
The divalent cation calcium potentiates the physiological response of neuronal nicotinic receptors to agonists by enhancing ionic current amplitudes, apparent agonist affinity and cooperativity. Here we show that mutations in...