J Michael Shipley
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Explore the profile of J Michael Shipley including associated specialties, affiliations and a list of published articles.
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26
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1482
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Recent Articles
11.
Lemaire R, Korn J, Shipley J, Lafyatis R
Arthritis Rheum
. 2005 Jun;
52(6):1812-23.
PMID: 15934076
Objective: Mutations in fibrillin 1, a key component of extracellular microfibrils, are associated with connective tissue disorders such as Marfan's syndrome or skin fibrosis in the tight skin mouse model...
12.
Lian X, Qin Y, Abu Hossain S, Yang L, White A, Xu H, et al.
J Immunol
. 2005 May;
174(11):7250-6.
PMID: 15905571
Acute lung injury is a side effect of therapy with a high concentration of inspired oxygen in patients. The molecular mechanism underlining this effect is poorly understood. In this study,...
13.
Nehring L, Miyamoto A, Hein P, Weinmaster G, Shipley J
J Biol Chem
. 2005 Mar;
280(21):20349-55.
PMID: 15788413
Elastic fibers are composed of the protein elastin and a network of 10-12-nm microfibrils, which are composed of several glycoproteins, including fibrillin-1, fibrillin-2, and MAGP1/2 (microfibril-associated glycoproteins-1 and -2). Although...
14.
Fernandez F, Campbell L, Liu W, Shipley J, Itohara S, Patterson G, et al.
Am J Transplant
. 2005 Mar;
5(4 Pt 1):671-83.
PMID: 15760390
This study was designed to define the roles of matrix metalloproteinase (MMP)-2 and MMP-9 in obliterative airway disease (OAD) in heterotopic murine tracheal allografts, considered a suitable animal model for...
15.
Campbell L, Ramachandran S, Liu W, Shipley J, Itohara S, Rogers J, et al.
Am J Transplant
. 2005 Feb;
5(3):517-28.
PMID: 15707406
Recent studies have shown an increased expression of several matrix metalloproteinases (MMP) during cardiac, renal and pulmonary allograft rejection. To further define the roles of MMP-2 and MMP-9 in the...
16.
Lemaire R, Farina G, Kissin E, Shipley J, Bona C, Korn J, et al.
Arthritis Rheum
. 2004 Mar;
50(3):915-26.
PMID: 15022335
Objective: Skin fibrosis in the TSK mouse, a model of skin fibrosis seen in systemic sclerosis (SSc), is caused by a large in-frame duplication in the Fbn1 gene, tsk-Fbn1. We...
17.
McMillan S, Kearley J, Campbell J, Zhu X, Larbi K, Shipley J, et al.
J Immunol
. 2004 Feb;
172(4):2586-94.
PMID: 14764732
Matrix metalloproteinases (MMPs) are a large family of endopeptidases that proteolytically degrade extracellular matrix. Many different cells produce MMP-9, and levels have been shown to be up-regulated in patients with...
18.
Krymskaya V, Shipley J
Am J Respir Cell Mol Biol
. 2003 Apr;
28(5):546-50.
PMID: 12707009
No abstract available.
19.
Galis Z, Johnson C, Godin D, Magid R, Shipley J, Senior R, et al.
Circ Res
. 2002 Nov;
91(9):852-9.
PMID: 12411401
Matrix remodeling plays an important role in the physiological and pathological remodeling of blood vessels. We specifically investigated the role of matrix metalloproteinase (MMP)-9, an MMP induced during arterial remodeling,...
20.
Hiratsuka S, Nakamura K, Iwai S, Murakami M, Itoh T, Kijima H, et al.
Cancer Cell
. 2002 Oct;
2(4):289-300.
PMID: 12398893
The molecular mechanism of tissue-specific metastasis in tumors endogenously expressing members of the vascular endothelial growth factor (VEGF) family is not yet clear. Here we demonstrate that MMP9 is specifically...