J Michael McDaniel
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Explore the profile of J Michael McDaniel including associated specialties, affiliations and a list of published articles.
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26
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1686
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Recent Articles
1.
Shao B, Hoover C, Shi H, Kondo Y, Lee R, Chen J, et al.
Blood
. 2022 Feb;
139(16):2523-2533.
PMID: 35157766
Microvascular thrombosis in patients with thrombotic thrombocytopenic purpura (TTP) is initiated by GPIbα-mediated platelet binding to von Willebrand factor (VWF). Binding of VWF to GPIbα causes activation of the platelet...
2.
Kondo Y, Larabee J, Gao L, Shi H, Shao B, Hoover C, et al.
JCI Insight
. 2021 Jul;
6(14).
PMID: 34291736
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a pandemic. Severe disease is associated with dysfunction of multiple organs, but some infected cells do...
3.
Jiang Y, Tang Y, Hoover C, Kondo Y, Huang D, Restagno D, et al.
Cell Death Differ
. 2021 May;
28(11):3009-3021.
PMID: 33993195
The liver has recently been identified as a major organ for destruction of desialylated platelets. However, the underlying mechanism remains unclear. Kupffer cells, which are professional phagocytic cells in the...
4.
Bergstrom K, Shan X, Casero D, Batushansky A, Lagishetty V, Jacobs J, et al.
Science
. 2020 Oct;
370(6515):467-472.
PMID: 33093110
Colon mucus segregates the intestinal microbiota from host tissues, but how it organizes to function throughout the colon is unclear. In mice, we found that colon mucus consists of two...
5.
Liu F, Fu J, Bergstrom K, Shan X, McDaniel J, McGee S, et al.
J Exp Med
. 2019 Oct;
217(1).
PMID: 31645367
Core 1-derived mucin-type O-glycans (O-glycans) are a major component of gastric mucus with an unclear role. To address this, we generated mice lacking gastric epithelial O-glycans (GEC C1galt1-/-). GEC C1galt1-/-...
6.
Yi J, Bergstrom K, Fu J, Shan X, McDaniel J, McGee S, et al.
Cell Death Differ
. 2018 Nov;
26(9):1656-1669.
PMID: 30478383
Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by defective intestinal barrier integrity toward the microbiota and epithelial damage. Double cortin-like kinase 1 (Dclk1), a marker of intestinal...
7.
Kondo Y, Fu J, Wang H, Hoover C, McDaniel J, Steet R, et al.
JCI Insight
. 2018 Jul;
3(14).
PMID: 30046013
Site-1 protease (S1P), encoded by MBTPS1, is a serine protease in the Golgi. S1P regulates lipogenesis, endoplasmic reticulum (ER) function, and lysosome biogenesis in mice and in cultured cells. However,...
8.
Song K, Fu J, Song J, Herzog B, Bergstrom K, Kondo Y, et al.
J Biol Chem
. 2017 Aug;
292(40):16491-16497.
PMID: 28842487
The kidney's filtration activity is essential for removing toxins and waste products from the body. The vascular endothelial cells of the glomerulus are fenestrated, flattened, and surrounded by podocytes, specialized...
9.
Li Y, Fu J, Ling Y, Yago T, McDaniel J, Song J, et al.
Proc Natl Acad Sci U S A
. 2017 Jul;
114(31):8360-8365.
PMID: 28716912
Most platelet membrane proteins are modified by mucin-type core 1-derived glycans (O-glycans). However, the biological importance of O-glycans in platelet clearance is unclear. Here, we generated mice with a hematopoietic...
10.
Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice
Bergstrom K, Liu X, Zhao Y, Gao N, Wu Q, Song K, et al.
Gastroenterology
. 2016 Apr;
151(1):152-164.e11.
PMID: 27059389
Background & Aims: Core 1- and core 3-derived mucin-type O-linked oligosaccharides (O-glycans) are major components of the colonic mucus layer. Defective forms of colonic O-glycans, such as the Thomsen-nouveau (Tn)...