J Lhomme
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Explore the profile of J Lhomme including associated specialties, affiliations and a list of published articles.
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47
Citations
383
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Recent Articles
1.
Lhomme J, Bouvier C, Mignot E, Paquier A
Water Sci Technol
. 2006 Nov;
54(6-7):83-91.
PMID: 17120637
A GIS-based one-dimensional flood simulation model is presented and applied to the centre of the city of Nîmes (Gard, France), for mapping flow depths or velocities in the streets network....
2.
Laayoun A, Sothier I, Menou L, Bernal-Mendez E, Kotera M, Bourget C, et al.
Nucleosides Nucleotides Nucleic Acids
. 2003 Oct;
22(5-8):649-52.
PMID: 14565245
A new and efficient strategy for labeling of nucleic acids prior to their hybridization on high density DNA chip has been developed. Our approach which combines the fragmentation and the...
3.
Garcia-Fresnadillo D, Boutonnet N, Schumm S, Moucheron C, Kirsch-De Mesmaeker A, Defrancq E, et al.
Biophys J
. 2002 Jan;
82(2):978-87.
PMID: 11806937
The yield of hole injection into guanines of different oligonucleotide duplexes by a photooxidizing tethered Ru(II) complex is examined by measuring the luminescence quenching of the excited complex. This yield...
4.
Charmantray F, Demeunynck M, Lhomme J, Duflos A
J Org Chem
. 2001 Nov;
66(24):8222-6.
PMID: 11722229
No abstract available.
5.
Forget D, Boturyn D, Defrancq E, Lhomme J, Dumy P
Chemistry
. 2001 Oct;
7(18):3976-84.
PMID: 11596939
A convergent strategy for the synthesis of peptide-oligonucleotide conjugates (POC) is presented. Chemoselective ligation of peptide to oligonucleotide was accomplished by oxime and thiazolidine formation. Oxime conjugation was performed by...
6.
Alarcon K, Demeunynck M, Lhomme J, Carrez D, Croisy A
Bioorg Med Chem Lett
. 2001 Jul;
11(14):1855-8.
PMID: 11459646
Three acridine-diaminopurine heterodimers tethered by a linker containing an N,N'-substituted guanidine were prepared. The molecules differ by the site of introduction of the linker on the 2,6-diaminopurine. The interactions of...
7.
Berthet N, Roupioz Y, Constant J, Kotera M, Lhomme J
Nucleic Acids Res
. 2001 Jul;
29(13):2725-32.
PMID: 11433017
A site-specifically modified oligonucleotide containing a single 2'-deoxyribonolactone lesion was used as a template for primer extension reactions catalyzed by M-MuLV reverse transcriptase (RT) and by the Klenow fragments of...
8.
Alarcon K, Demeunynck M, Lhomme J, Carrez D, Croisy A
Bioorg Med Chem
. 2001 Jun;
9(7):1901-10.
PMID: 11425593
We describe the synthesis, DNA binding measurements and pharmacological properties of a series of new heterodimeric molecules, in which a 2,6-diaminopurine is linked to a 9-aminoacridine chromophore. The linking chain...
9.
Defrancq E, Lhomme J
Bioorg Med Chem Lett
. 2001 Apr;
11(7):931-3.
PMID: 11294394
We describe the preparation of oligonucleotides containing a 5'-linker bearing an aminooxy group. Use of the trityl protecting group for the aminooxy moiety allows purification of the modified oligonucleotide by...
10.
Trevisiol E, Renard A, Defrancq E, Lhomme J
Nucleosides Nucleotides Nucleic Acids
. 2000 Nov;
19(9):1427-39.
PMID: 11092313
We describe the reaction of oligonucleotides containing an aldehydic group at the 5'-end or inside the sequence with an oxyamino label. The reaction was found to be highly selective and...