J K Kumar
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Explore the profile of J K Kumar including associated specialties, affiliations and a list of published articles.
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24
Citations
271
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Recent Articles
1.
Kashyap H, Kumar J, Kandavel T, Reddy Y
Acta Psychiatr Scand
. 2012 Mar;
126(2):106-14.
PMID: 22375841
Objective: There are limited data on neuropsychological correlates of poor insight in obsessive-compulsive disorder (OCD). We hypothesize that poor insight may be associated with greater impairment in tasks of conflict...
2.
Chanda D, Saikia D, Kumar J, Thakur J, Agarwal J, Chanotiya C, et al.
Bioorg Med Chem Lett
. 2011 Jun;
21(13):3966-9.
PMID: 21641212
1-Chloro-2-formyl indenes and tetralenes have been synthesized using Vilsmeier-Haack-Arnold reaction onto indanones and tetralones. Most of these analogues exhibited antitubercular activity against Mycobacterium tuberculosis H37Rv strain with MICs ranging from...
3.
Saikia D, Parihar S, Chanda D, Ojha S, Kumar J, Chanotiya C, et al.
Bioorg Med Chem Lett
. 2009 Dec;
20(2):508-12.
PMID: 20004575
Phytol, a diterpene alcohol was modified to several semisynthetic analogues. Some of the modifications were done logically to enhance lipophilicity of the molecule. Analogues 14, 16 and 18 exhibited antitubercular...
4.
Fatima A, Gupta V, Luqman S, Negi A, Kumar J, Shanker K, et al.
Phytother Res
. 2009 Jan;
23(8):1190-3.
PMID: 19170157
Glabridin, an active constituent of Glycyrrhiza glabra roots, was found to be active against both yeast and filamentous fungi. Glabridin also showed resistance modifying activity against drug resistant mutants of...
5.
Saxena H, Faridi U, Srivastava S, Kumar J, Darokar M, Luqman S, et al.
Bioorg Med Chem Lett
. 2008 Jul;
18(14):3914-8.
PMID: 18586491
Gallic acid-based indanone derivatives have been synthesised. Some of the indanones showed very good anticancer activity in MTT assay. Compounds 10, 11, 12 and 14 possessed potent anticancer activity against...
6.
Gupta V, Fatima A, Faridi U, Negi A, Shanker K, Kumar J, et al.
J Ethnopharmacol
. 2008 Jan;
116(2):377-80.
PMID: 18182260
The present study was aimed to investigate antimicrobial potential of Glycyrrhiza glabra roots. Antimycobacterial activity of Glycyrrhiza glabra was found at 500 microg/mL concentration. Bioactivity guided phytochemical analysis identified glabridin...
7.
Negi A, Kumar J, Luqman S, Shanker K, Gupta M, Khanuja S
Med Res Rev
. 2007 Nov;
28(5):746-72.
PMID: 17979145
Medicinal plants have been traditionally used for treating liver diseases since centuries. Several leads from plant sources have been found as potential hepatoprotective agents with diverse chemical structures. Although, a...
8.
Saxena H, Faridi U, Kumar J, Luqman S, Darokar M, Shanker K, et al.
Steroids
. 2007 Sep;
72(13):892-900.
PMID: 17850837
Chalcone derivatives on estradiol framework have been synthesized. Some of the derivatives showed potent anticancer activity against some human cancer cell lines. Compounds 9 and 19 showed potent activity against...
9.
Srivastava V, Darokar M, Fatima A, Kumar J, Chowdhury C, Saxena H, et al.
Bioorg Med Chem
. 2006 Oct;
15(1):518-25.
PMID: 17035037
Several diverse analogues of Oenostacin, a naturally occurring potent antibacterial phenolic acid derivative, have been synthesized. A small library with more than forty analogues having different aromatic rings and varied...
10.
Srivastava V, Saxena H, Shanker K, Kumar J, Luqman S, Gupta M, et al.
Bioorg Med Chem Lett
. 2006 Jun;
16(17):4603-8.
PMID: 16797987
Gallic acid, one of the most abundant plant phenolic acids, has been modified to cathepsin D protease inhibitors. The strategy of modification was proposed basing on some previously reported structure...