J Janin
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Explore the profile of J Janin including associated specialties, affiliations and a list of published articles.
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132
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4234
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Recent Articles
1.
Bernauer J, Aze J, Janin J, Poupon A
Bioinformatics
. 2007 Jan;
23(5):555-62.
PMID: 17237048
Motivation: Protein-protein complexes are known to play key roles in many cellular processes. However, they are often not accessible to experimental study because of their low stability and difficulty to...
2.
Hillaireau H, Le Doan T, Chacun H, Janin J, Couvreur P
Int J Pharm
. 2006 Dec;
331(2):148-52.
PMID: 17150318
In a previous study, we have shown that cidofovir (CDV) and azidothymidine-triphosphate (AZT-TP) were poorly encapsulated in poly(iso-butylcyanoacrylate) (PIBCA) aqueous-core nanocapsules. This was attributed to the rapid leakage of these...
3.
Hillaireau H, Le Doan T, Besnard M, Chacun H, Janin J, Couvreur P
Int J Pharm
. 2006 Aug;
324(1):37-42.
PMID: 16935444
Nucleoside analogues are widely used in the treatment of various viral infections. However, the poor in vivo conversion of the nucleoside analogues like azidothymidine (AZT) into their active triphosphate nucleotide...
4.
Chen Y, Morera S, Pasti C, Angusti A, Solaroli N, Veron M, et al.
Med Chem
. 2006 Jun;
1(6):529-36.
PMID: 16787337
NDP kinase catalyzes the last step in the phosphorylation of nucleotides. It is also involved in the activation by cellular kinases of nucleoside analogs used in antiviral therapies. Adenosine phosphonoacetic...
5.
Graille M, Meyer P, Leulliot N, Sorel I, Janin J, van Tilbeurgh H, et al.
Biochimie
. 2005 Aug;
87(8):763-9.
PMID: 16054529
Ribose-5-phosphate isomerase A has an important role in sugar metabolism by interconverting ribose-5-phosphate and ribulose-5-phosphate. This enzyme is ubiquitous and highly conserved among the three kingdoms of life. We have...
6.
Janin J, Dumas C, Morera S, Xu Y, Meyer P, Chiadmi M, et al.
J Bioenerg Biomembr
. 2002 Jan;
32(3):215-25.
PMID: 11768305
Three-dimensional structures are known from X-ray studies of the nucleoside diphosphate (NDP) kinase of many organisms from bacteria to human. All NDP kinases have subunits of about 150 residues with...
7.
Schneider B, Meyer P, Sarfati S, Mulard L, Guerreiro C, Boretto J, et al.
Nucleosides Nucleotides Nucleic Acids
. 2001 Sep;
20(4-7):297-306.
PMID: 11563041
Nucleoside activation by nucleoside diphosphate kinase and inhibition of HIV-1 reverse transcriptase were studied comparatively for a new class of nucleoside analogs with a borano (BH3-) or a thio (SH)...
8.
Nadassy K, Tomas-Oliveira I, Alberts I, Janin J, Wodak S
Nucleic Acids Res
. 2001 Aug;
29(16):3362-76.
PMID: 11504874
Standard volumes for atoms in double-stranded B-DNA are derived using high resolution crystal structures from the Nucleic Acid Database (NDB) and compared with corresponding values derived from crystal structures of...
9.
Morera S, Lariviere L, Kurzeck J, Freemont P, Janin J, Ruger W
J Mol Biol
. 2001 Aug;
311(3):569-77.
PMID: 11493010
beta-Glucosyltransferase (BGT) is a DNA-modifying enzyme encoded by bacteriophage T4 that transfers glucose from uridine diphosphoglucose to 5-hydroxymethyl cytosine bases of phage T4 DNA. We report six X-ray structures of...
10.
Fieulaine S, Morera S, Poncet S, Monedero V, Gueguen-Chaignon V, Galinier A, et al.
EMBO J
. 2001 Aug;
20(15):3917-27.
PMID: 11483495
HPr kinase/phosphatase (HprK/P) is a key regulatory enzyme controlling carbon metabolism in Gram- positive bacteria. It catalyses the ATP-dependent phosphorylation of Ser46 in HPr, a protein of the phosphotransferase system,...