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J CHERFILS

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Articles 37
Citations 884
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Recent Articles
1.
Hible G, Daalova P, Gilles A, CHERFILS J
Biochimie . 2006 May; 88(9):1157-64. PMID: 16690197
Guanosine monophosphate kinases (GMPK), by catalyzing the phosphorylation of GMP or dGMP, are of dual potential in assisting the activation of anti-viral prodrugs or as candidates for antibiotic strategies. Human...
2.
Zeghouf M, Guibert B, Zeeh J, CHERFILS J
Biochem Soc Trans . 2005 Oct; 33(Pt 6):1265-8. PMID: 16246094
GEFs (guanine nucleotide-exchange factors), which stimulate GDP dissociation from small G-proteins, are pivotal regulators of signalling pathways activated by small G-proteins. In the case of Arf proteins, which are major...
3.
CHERFILS J, Melancon P
Biochem Soc Trans . 2005 Jul; 33(Pt 4):635-8. PMID: 16042561
Arf (ADP-ribosylation factor) proteins form a special class of small GTP-binding proteins in that their activation by GDP/GTP exchange is coupled to their recruitment to membranes using a built-in structural...
4.
Dransart E, Morin A, CHERFILS J, Olofsson B
Biochem Soc Trans . 2005 Jul; 33(Pt 4):623-6. PMID: 16042558
rhoGDIs (Rho GDP dissociation inhibitors) are postulated to regulate the activity and the localization of small G-proteins of the Rho family by a shuttling process involving extraction of Rho from...
5.
Janin J, Dumas C, Morera S, Xu Y, Meyer P, Chiadmi M, et al.
J Bioenerg Biomembr . 2002 Jan; 32(3):215-25. PMID: 11768305
Three-dimensional structures are known from X-ray studies of the nucleoside diphosphate (NDP) kinase of many organisms from bacteria to human. All NDP kinases have subunits of about 150 residues with...
6.
CHERFILS J
FEBS Lett . 2001 Nov; 507(3):280-4. PMID: 11696355
Small G proteins cycle between an inactive form bound to GDP, and an active form bound to GTP. The two forms have different conformations and interact specifically with different partners,...
7.
Erent M, Gonin P, CHERFILS J, Tissier P, Raschella G, Giartosio A, et al.
Eur J Biochem . 2001 Mar; 268(7):1972-81. PMID: 11277919
The human DRnm23 gene was identified by differential screening of a cDNA library obtained from chronic myeloid leukaemia-blast crisis primary cells. The over-expression of this gene inhibits differentiation and induces...
8.
Pasqualato S, Menetrey J, Franco M, CHERFILS J
EMBO Rep . 2001 Mar; 2(3):234-8. PMID: 11266366
The small GTP-binding protein Arf6 coordinates membrane traffic at the plasma membrane with aspects of cytoskeleton organization. This function does not overlap with that of other members of the ADP-ribosylation...
9.
Renault L, Kerjan P, Pasqualato S, Menetrey J, Robinson J, Kawaguchi S, et al.
EMBO J . 2001 Feb; 20(3):570-8. PMID: 11157763
The EMAPII (endothelial monocyte-activating polypeptide II) domain is a tRNA-binding domain associated with several aminoacyl-tRNA synthetases, which becomes an independent domain with inflammatory cytokine activity upon apoptotic cleavage from the...
10.
Menetrey J, Macia E, Pasqualato S, Franco M, CHERFILS J
Nat Struct Biol . 2000 Jul; 7(6):466-9. PMID: 10881192
Arf6 is an isoform of Arf that localizes at the periphery of the cell where it has an essential role in endocytotic pathways. Its function does not overlap with that...