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J J Mule

Explore the profile of J J Mule including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 94
Citations 2555
Followers 0
Related Specialties
Allergy & Immunology
Oncology
Pharmacology
Top 10 Co-Authors
S A Rosenberg
N P Restifo
J K McIntosh
K Shimizu
J C Yang
A L Asher
S Shu
E Shiloni
P J Spiess
D L Jicha
Published In
J Immunol
Cancer Res
J Exp Med
Cancer Immunol Immunother
Hum Gene Ther
Affiliations
Soon will be listed here.
Recent Articles
1.
Dendritic cell-based vaccines for cancer therapy
Grolleau A, Sloan A, Mule J
Cancer Treat Res . 2005 Oct; 123:181-205. PMID: 16211871
No abstract available.
2.
Augmentation of antitumor immune responses after adoptive transfer of bone marrow derived from donors immunized with tumor lysate-pulsed dendritic cells
Asavaroengchai W, Kotera Y, Koike N, Pilon-Thomas S, Mule J
Biol Blood Marrow Transplant . 2004 Jul; 10(8):524-33. PMID: 15282530
We demonstrated previously that tumor lysate-pulsed dendritic cells (TP-DC) could mediate a specific and long-lasting antitumor immune response against a weakly immunogenic breast tumor during early lymphoid reconstitution. The purpose...
3.
Tumor lysate-pulsed dendritic cells can elicit an effective antitumor immune response during early lymphoid recovery
Asavaroengchai W, Kotera Y, Mule J
Proc Natl Acad Sci U S A . 2002 Jan; 99(2):931-6. PMID: 11792864
Dendritic cells (DC) can serve to immunize the newborn immune system to foreign antigen. In a lymphopenic environment, naive T cells undergoing homeostasis-driven proliferation can acquire increased sensitivity to antigen...
4.
The dynamics of the T-cell antitumor response: chemokine-secreting dendritic cells can prime tumor-reactive T cells extranodally
Kirk C, Mule J
Cancer Res . 2001 Dec; 61(24):8794-802. PMID: 11751401
Direct administration of dendritic cells (DCs) genetically modified to express secondary lymphoid tissue chemokine (SLC) into growing B16 melanoma could result in a substantial, sustained influx of T cells within...
5.
Immune evasion by muscle-specific gene expression in dystrophic muscle
Kirk C, Crawford R, Mule J, Chamberlain J
Mol Ther . 2001 Dec; 4(6):525-33. PMID: 11735336
Muscle tissue from Duchenne muscular dystrophy patients and the Dmd(mdx/mdx) (hereafter referred to as mdx) mouse is characterized by an abundance of necrotic myofibers and infiltrating macrophages. Both features may...
6.
Vaccination of pediatric solid tumor patients with tumor lysate-pulsed dendritic cells can expand specific T cells and mediate tumor regression
Geiger J, Hutchinson R, Hohenkirk L, McKenna E, Yanik G, Levine J, et al.
Cancer Res . 2001 Dec; 61(23):8513-9. PMID: 11731436
Dendritic cells (DCs) have been shown to be a promising adjuvant for inducing immunity to cancer. We evaluated tumor lysate-pulsed DC in a Phase I trial of pediatric patients with...
7.
Comparative analysis of necrotic and apoptotic tumor cells as a source of antigen(s) in dendritic cell-based immunization
Kotera Y, Shimizu K, Mule J
Cancer Res . 2001 Nov; 61(22):8105-9. PMID: 11719436
There is considerable controversy as to whether necrotic (lysate) or apoptotic tumor cells serve as the superior source of multiple tumor-associated antigens (TAAs) to pulse dendritic cells (DCs) for immunotherapeutic...
8.
Dendritic cells genetically engineered to express IL-4 inhibit murine collagen-induced arthritis
Morita Y, Yang J, Gupta R, Shimizu K, Shelden E, Endres J, et al.
J Clin Invest . 2001 May; 107(10):1275-84. PMID: 11375417
Dendritic cells (DCs) are specialized antigen-presenting cells that migrate from the periphery to lymphoid tissues, where they activate and regulate T cells. Genetic modification of DCs to express immunoregulatory molecules...
9.
Enhancement of tumor lysate- and peptide-pulsed dendritic cell-based vaccines by the addition of foreign helper protein
Shimizu K, Thomas E, Giedlin M, Mule J
Cancer Res . 2001 Apr; 61(6):2618-24. PMID: 11289139
We have evaluated whether the addition of a foreign helper protein, keyhole limpet hemocyanin (KLH), can augment the efficacy of tumor lysate-pulsed dendritic cells and peptide-pulsed DC immunizations in vivo....
10.
T cell-dependent antitumor immunity mediated by secondary lymphoid tissue chemokine: augmentation of dendritic cell-based immunotherapy
Kirk C, Nickoloff B, Chamberlain J, Giedlin M, Aukerman L, Mule J
Cancer Res . 2001 Mar; 61(5):2062-70. PMID: 11280767
Secondary lymphoid tissue chemokine (SLC) is a CC chemokine that is selective in its recruitment of naive T cells and dendritic cells (DCs). In the lymph node, SLC is believed...