J Hanoune
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Explore the profile of J Hanoune including associated specialties, affiliations and a list of published articles.
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182
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2209
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Recent Articles
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Tzavara E, Monory K, GAREL S, Topilko P, Charnay P, Hanoune J
Neuroreport
. 2001 Jun;
12(7):1367-70.
PMID: 11388413
Krox-24 is an immediate early gene encoding a zinc-finger transcription factor implicated in several adaptive responses, and its induction by cannabinoids has been reported. We used mice targeted in the...
3.
Hanoune J, Defer N
Annu Rev Pharmacol Toxicol
. 2001 Mar;
41:145-74.
PMID: 11264454
At least nine closely related isoforms of adenylyl cyclases (ACs), the enzymes responsible for the synthesis of cyclic AMP (cAMP) from ATP, have been cloned and characterized in mammals. Depending...
4.
Szikra J, Benyhe S, Orosz G, Darula Z, Piot J, Fruitier I, et al.
Biochem Biophys Res Commun
. 2001 Mar;
281(3):670-7.
PMID: 11237710
Receptor binding properties of the hemoglobin-derived nonapeptide VV-hemorphin 7 (Val-Val-Tyr-Pro-Trp-Thr-Gln-Arg-Phe-OH) were studied using both the unlabelled form and tritium-labelled derivative of the peptide. In binding studies using selective opioid radioligands,...
5.
Vanvooren V, Allgeier A, Cosson E, Van Sande J, Defer N, Pirlot M, et al.
Mol Cell Endocrinol
. 2001 Feb;
170(1-2):185-96.
PMID: 11162902
Although the TSH receptor and Galpha(s), which activate the cAMP cascade in the thyroid gland have been much studied, nothing is known about the adenylyl cyclase (AC) isoforms which are...
6.
Defer N, Hanoune J
Am J Physiol Renal Physiol
. 2000 Sep;
279(3):F400-16.
PMID: 10966920
The present review focuses on the potential physiological regulations involving different isoforms of adenylyl cyclase (AC), the enzymatic activity responsible for the synthesis of cAMP from ATP. Depending on the...
7.
Lipskaia L, Defer N, Esposito G, Hajar I, Garel M, Rockman H, et al.
Circ Res
. 2000 Apr;
86(7):795-801.
PMID: 10764414
The predominant functional adenylyl cyclases normally expressed in cardiac tissue and coupled to beta-adrenergic receptors are inhibited by micromolar Ca(2+) concentration. To modify the overall balance of activities, we have...
8.
Tzavara E, Valjent E, Firmo C, Mas M, Beslot F, Defer N, et al.
Eur J Neurosci
. 2000 Apr;
12(3):1038-46.
PMID: 10762335
Region-specific up-regulation of the cyclic AMP pathway is considered an important molecular mechanism in the origin of the somatic manifestations of the withdrawal syndrome to known drugs of abuse. Nevertheless,...
9.
Monory K, Bourin M, Spetea M, Tomboly C, Toth G, Matthes H, et al.
Eur J Neurosci
. 2000 Mar;
12(2):577-84.
PMID: 10712637
The recently discovered endomorphin 1 (Tyr-Pro-Trp-Phe-NH2) and endomorphin 2 (Tyr-Pro-Phe-Phe-NH2) were investigated with respect to their direct receptor-binding properties, and to their ability to activate G proteins and to inhibit...
10.
Mamluk R, Defer N, Hanoune J, Meidan R
Endocrinology
. 1999 Sep;
140(10):4601-8.
PMID: 10499516
The involvement of cAMP in various aspects of ovarian steroidogenic cells functions has been extensively studied. However, the adenylyl cyclase (AC) types expressed in ovarian cells, of any species, are...