J G Christenson
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Explore the profile of J G Christenson including associated specialties, affiliations and a list of published articles.
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18
Citations
199
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Recent Articles
1.
Kelly K, Rubin R, Williams Jr W, Meehan S, Meschter C, Christenson J, et al.
Am J Physiol
. 1996 Nov;
271(5 Pt 2):F1061-7.
PMID: 8946001
The role of platelet-activating factor (PAF) in ischemic acute renal failure was evaluated by administering an oral PAF antagonist (Ro-24-4736) to rats prior to or after interruption of blood flow...
2.
Albrecht H, Beskid G, Christenson J, Deitcher K, Georgopapadakou N, Keith D, et al.
J Med Chem
. 1994 Feb;
37(3):400-7.
PMID: 8308866
We have previously reported that linking quinolones to the cephalosporin 3'-position through an ester bond, a carbamate function, or a bond through a quaternary nitrogen produced cephalosporins with a dual...
3.
Albrecht H, Beskid G, Christenson J, Georgopapadakou N, Keith D, Konzelmann F, et al.
J Med Chem
. 1991 Sep;
34(9):2857-64.
PMID: 1910090
A series of cephalosporins has been prepared in which the 3'-position was linked to the nitrogen of the antibacterial quinolone ciprofloxacin through a carbamate function. Like the ester-linked and quaternary-linked...
4.
Albrecht H, Beskid G, Christenson J, Durkin J, Fallat V, Georgopapadakou N, et al.
J Med Chem
. 1991 Feb;
34(2):669-75.
PMID: 1847430
When cephalosporins exert their biological activity by reacting with bacterial enzymes, opening of the beta-lactam ring can lead to expulsion of the 3'-substituent. A series of cephalosporins was prepared in...
5.
Christenson J, Chan K, Cleeland R, Farrish Jr H, Patel I, Specian A
Antimicrob Agents Chemother
. 1990 Oct;
34(10):1895-900.
PMID: 2127171
Ro 23-9424 is a dual-action cephalosporin with an aminothiazolylmethoxyimino-type side chain at the 7 position and fleroxacin esterified at the 3' position. The new compound has broad and potent antibacterial...
6.
Albrecht H, Beskid G, Chan K, Christenson J, Cleeland R, Deitcher K, et al.
J Med Chem
. 1990 Jan;
33(1):77-86.
PMID: 2153215
According to the generally accepted mechanism by which bacterial enzymes react with cephalosporins, opening of the beta-lactam ring can lead to the expulsion of a 3'-substituent. A series of dual-action...
7.
Talbot M, Schaefer F, Brocks V, Christenson J
Antimicrob Agents Chemother
. 1989 Dec;
33(12):2101-8.
PMID: 2515794
The recovery of peptidoglycan-synthesizing activity after inhibition by beta-lactam antibiotics was investigated in ether-permeabilized cells of Escherichia coli B. Such cells synthesize sodium dodecyl sulfate-insoluble peptidoglycan when provided with UDP-linked...
8.
Christenson J, PRUESS D, Talbot M, Keith D
Antimicrob Agents Chemother
. 1988 Jul;
32(7):1005-11.
PMID: 3190190
The penam nucleus can assume two conformations; these are designated open and closed. The synthetic (2,3)-alpha- and (2,3)-beta-methylenepenams can be regarded as analogs of the open and closed conformations, respectively....
9.
Neu H, Srinivasan S, Francke E, Christenson J
Am J Med
. 1983 Aug;
75(2A):60-4.
PMID: 6311007
The pharmacokinetic parameters of amdinocillin and pivamdinocillin were studied in 12 normal volunteers. Plasma amdinocillin concentrations were determined by microbiologic assay and urine concentrations by high performance liquid chromatography. Pharmacokinetic...
10.
ISENBERG H, Cleeland R, TITSWORTH E, Beskid G, Christenson J, DELORENZO W, et al.
Crit Rev Microbiol
. 1982 Jan;
10(1):1-76.
PMID: 6756787
Recent clinical isolates (approximately 150 strains) of the family Enterobacteriaceae were examined by agar diffusion, microdilution, and the Autobac automated system for their responses to beta-lactam antibiotics singly and in...