J D Sweatt
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Explore the profile of J D Sweatt including associated specialties, affiliations and a list of published articles.
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68
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4511
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Recent Articles
1.
Greer C, Wright J, Weiss J, Lazarenko R, Moran S, Zhu J, et al.
J Neurosci
. 2020 Dec;
41(4):578-593.
PMID: 33262245
The dynamic regulation of DNA methylation in postmitotic neurons is necessary for memory formation and other adaptive behaviors. Ten-eleven translocation 1 (TET1) plays a part in these processes by oxidizing...
2.
Penner M, Roth T, Chawla M, Hoang L, Roth E, Lubin F, et al.
Neurobiol Aging
. 2010 Mar;
32(12):2198-210.
PMID: 20189687
The transcription of genes that support memory processes are likely to be impacted by the normal aging process. Because Arc is necessary for memory consolidation and enduring synaptic plasticity, we...
3.
Levenson J, Sweatt J
Cell Mol Life Sci
. 2006 Apr;
63(9):1009-16.
PMID: 16596331
In this review we address the idea that conservation of epigenetic mechanisms for information storage represents a unifying model in biology, with epigenetic mechanisms being utilized for cellular memory at...
4.
Lubin F, Johnston L, Sweatt J, Anderson A
Neuroscience
. 2005 May;
133(4):969-81.
PMID: 15916859
The transcription factor nuclear factor-kappa B (NF-kappaB) is an inducible regulator of genes that plays a crucial role in the nervous system. Glutamate receptor stimulation is one well-described mechanism for...
5.
Birnbaum S, Yuan P, Wang M, Vijayraghavan S, Bloom A, DAVIS D, et al.
Science
. 2004 Oct;
306(5697):882-4.
PMID: 15514161
The prefrontal cortex is a higher brain region that regulates thought, behavior, and emotion using representational knowledge, operations often referred to as working memory. We tested the influence of protein...
6.
Wang R, Dineley K, Sweatt J, Zheng H
Neuroscience
. 2004 Jun;
126(2):305-12.
PMID: 15207348
Alzheimer's disease is a learning and memory disorder pathologically characterized by the deposition of beta-amyloid plaques and loss of neurons and synapses in affected areas of the brain. Mutations in...
7.
Sweatt J
Neuron
. 2001 Sep;
31(5):671-4.
PMID: 11567607
Studies of the signal transduction mechanisms underlying learning and memory have provided many new insights into the molecular mechanisms underlying associative conditioning in mammals. In this issue of Neuron, Gean...
8.
9.
Dineley K, Westerman M, Bui D, Bell K, Ashe K, Sweatt J
J Neurosci
. 2001 Jun;
21(12):4125-33.
PMID: 11404397
Alzheimer's Disease (AD) is the most common of the senile dementias, the prevalence of which is increasing rapidly, with a projected 14 million affected worldwide by 2025. The signal transduction...
10.
Sweatt J
Curr Biol
. 2001 May;
11(10):R391-4.
PMID: 11378403
Protein phosphorylation has long been known to play a key role in triggering the synaptic changes underlying learning and memory. Recent studies highlight the importance of tightly regulated dephosphorylation as...