J C Fiddes
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Explore the profile of J C Fiddes including associated specialties, affiliations and a list of published articles.
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2487
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Recent Articles
1.
Fiddes J
Curr Opin Drug Discov Devel
. 2009 Aug;
3(5):655.
PMID: 19649894
Protegrins are 16 to 18 amino acid, cationic antimicrobial peptides that are produced by porcine neutrophils, and are activated extracellularly by cleavage of the pro-protegrin molecule by neutrophil elastase. Biologically,...
2.
Chen J, Falla T, Liu H, Hurst M, Fujii C, Mosca D, et al.
Biopolymers
. 2000 Aug;
55(1):88-98.
PMID: 10931444
Protegrin antimicrobial peptides possess activity against gram-positive and gram-negative bacteria and yeasts. An extensive structure-activity relationship (SAR) study was conducted on several hundred protegrin analogues to gain understanding of the...
3.
Loury D, Embree J, Steinberg D, Sonis S, Fiddes J
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
. 1999 May;
87(5):544-51.
PMID: 10348510
Objective: The purpose of this animal study was to determine whether IB-367, an antimicrobial peptide, is able to ameliorate oral mucositis by reducing microflora densities on the mucosal surfaces of...
4.
Steinberg D, Hurst M, Fujii C, Kung A, Ho J, Cheng F, et al.
Antimicrob Agents Chemother
. 1997 Aug;
41(8):1738-42.
PMID: 9257752
Protegrin-1 (PG-1) is a cysteine-rich, 18-residue beta-sheet peptide isolated from porcine leukocytes with antimicrobial activity against a broad range of microorganisms. The MICs of PG-1 against representative gram-positive and gram-negative...
5.
Tischer E, Mitchell R, Hartman T, Silva M, GOSPODAROWICZ D, Fiddes J, et al.
J Biol Chem
. 1991 Jun;
266(18):11947-54.
PMID: 1711045
Vascular endothelial growth factor (VEGF) is an apparently endothelial cell-specific mitogen that is structurally related to platelet-derived growth factor. By Northern blot and protein analyses, we show that VEGF is...
6.
Higashiyama S, Abraham J, Miller J, Fiddes J, Klagsbrun M
Science
. 1991 Feb;
251(4996):936-9.
PMID: 1840698
Macrophage-like U-937 cells secrete a 22-kilodalton heparin-binding growth factor that is mitogenic for BALB-3T3 fibroblasts and smooth muscle cells, but not endothelial cells. The amino acid sequence predicted from complementary...
7.
Klingbeil C, Cesar L, Fiddes J
Prog Clin Biol Res
. 1991 Jan;
365:443-58.
PMID: 1862149
No abstract available.
8.
Thompson S, Protter A, Bitting L, Fiddes J, Abraham J
Methods Enzymol
. 1991 Jan;
198:96-116.
PMID: 1857242
No abstract available.
9.
10.
Fiddes J, Hebda P, Hayward P, ROBSON M, Abraham J, Klingbeil C
Ann N Y Acad Sci
. 1991 Jan;
638:316-28.
PMID: 1785809
No abstract available.