J Alejandro Lopez
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Explore the profile of J Alejandro Lopez including associated specialties, affiliations and a list of published articles.
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31
Citations
883
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Recent Articles
11.
Sinha D, Kalimutho M, Bowles J, Chan A, Merriner D, Bain A, et al.
FASEB J
. 2018 Apr;
32(9):4984-4999.
PMID: 29683733
Spermatogenesis is a dynamic process involving self-renewal and differentiation of spermatogonial stem cells, meiosis, and ultimately, the differentiation of haploid spermatids into sperm. Centrosomal protein 55 kDa (CEP55) is necessary...
12.
Ng S, Souza-Fonseca-Guimaraes F, De Labastida Rivera F, Amante F, Kumar R, Gao Y, et al.
Clin Transl Immunology
. 2018 Feb;
7(1):e1003.
PMID: 29484181
Objectives: Innate lymphoid cells (ILCs) share many characteristics with CD4 T cells, and group 1 ILCs share a requirement for T-bet and the ability to produce IFNγ with T helper...
13.
Jimenez R, Ikonomopoulou M, Lopez J, Miles J
Toxicon
. 2017 Nov;
141:18-24.
PMID: 29170055
This review catalogues recent advances in knowledge on venoms as standalone therapeutic agents or as blueprints for drug design, with an emphasis on venom-derived compounds that affects the immune system....
14.
Kalimutho M, Parsons K, Mittal D, Lopez J, Srihari S, Khanna K
Trends Pharmacol Sci
. 2015 Nov;
36(12):822-846.
PMID: 26538316
Triple-negative breast cancers (TNBCs) constitute a heterogeneous subtype of breast cancers that have a poor clinical outcome. Although no approved targeted therapy is available for TNBCs, molecular-profiling efforts have revealed...
15.
Pritchard A, Burel J, Neller M, Hayward N, Lopez J, Fatho M, et al.
Cancer Immunol Res
. 2015 Jun;
3(9):992-8.
PMID: 26048577
The ability to use circulating peripheral blood cells and matched tumor sequencing data as a basis for neoantigen prediction has exciting possibilities for application in the personalized treatment of cancer...
16.
Pinzon-Charry A, Woodberry T, Kienzle V, McPhun V, Minigo G, Lampah D, et al.
J Exp Med
. 2013 Jul;
210(8):1635-46.
PMID: 23835848
Malaria causes significant morbidity worldwide and a vaccine is urgently required. Plasmodium infection causes considerable immune dysregulation, and elicitation of vaccine immunity remains challenging. Given the central role of dendritic...
17.
Smart C, Morrison B, Saunus J, Vargas A, Keith P, Reid L, et al.
PLoS One
. 2013 Jun;
8(6):e64388.
PMID: 23750209
Mammosphere and breast tumoursphere culture have gained popularity as in vitro assays for propagating and analysing normal and cancer stem cells. Whether the spheres derived from different sources or parent...
18.
Morrison B, Hastie M, Grewal Y, Bruce Z, Schmidt C, Reynolds B, et al.
PLoS One
. 2013 Jan;
7(12):e52692.
PMID: 23285151
Breast cancer is a heterogeneous disease, composed of tumour cells with differing gene expressions and phenotypes. Very few antigens have been identified and a better understanding of tumour initiating-cells as...
19.
Woodberry T, Minigo G, Piera K, Amante F, Pinzon-Charry A, Good M, et al.
J Infect Dis
. 2012 May;
206(3):333-40.
PMID: 22615323
Background: Dendritic cells (DCs) are highly specialized antigen-presenting cells that are crucial for initiation of immune responses. During naturally acquired malaria, DC number and function is reduced. Methods: The timing...
20.
Hayes S, Di Sipio T, Rye S, Lopez J, Saunders C, Pyke C, et al.
Lymphat Res Biol
. 2011 Nov;
9(3):135-41.
PMID: 22066743
Background: The adverse consequences of lymphedema following breast cancer in relation to physical function and quality of life are clear; however, its potential relationship with survival has not been investigated....