Ivan R Correa Jr
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Explore the profile of Ivan R Correa Jr including associated specialties, affiliations and a list of published articles.
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Articles
77
Citations
2407
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Recent Articles
21.
Marzook A, Chen S, Pickford P, Lucey M, Wang Y, Correa Jr I, et al.
Biochem Pharmacol
. 2021 Jun;
190:114656.
PMID: 34129856
The glucagon-like peptide-1 receptor (GLP-1R) is an important regulator of glucose homeostasis and has been successfully targeted for the treatment of type 2 diabetes. Recently described biased GLP-1R agonists with...
22.
Sun Z, Vaisvila R, Hussong L, Yan B, Baum C, Saleh L, et al.
Genome Res
. 2021 Jan;
31(2):291-300.
PMID: 33468551
The predominant methodology for DNA methylation analysis relies on the chemical deamination by sodium bisulfite of unmodified cytosine to uracil to permit the differential readout of methylated cytosines. Bisulfite treatment...
23.
Jones B, McGlone E, Fang Z, Pickford P, Correa Jr I, Oishi A, et al.
J Biol Chem
. 2020 Dec;
296:100133.
PMID: 33268378
Receptors for the peptide hormones glucagon-like peptide-1 (GLP-1R), glucose-dependent insulinotropic polypeptide (GIPR), and glucagon (GCGR) are important regulators of insulin secretion and energy metabolism. GLP-1R agonists have been successfully deployed...
24.
Flodman K, Correa Jr I, Dai N, Weigele P, Xu S
Front Microbiol
. 2020 Nov;
11:604618.
PMID: 33193286
To counteract host-encoded restriction systems, bacteriophages (phages) incorporate modified bases in their genomes. For example, phages carry in their genomes modified pyrimidines such as 5-hydroxymethyl-cytosine (5hmC) in T4 deficient in...
25.
Fang Z, Chen S, Manchanda Y, Bitsi S, Pickford P, David A, et al.
Int J Mol Sci
. 2020 Nov;
21(21).
PMID: 33182425
The glucagon-like peptide-1 receptor (GLP-1R) is an important regulator of blood glucose homeostasis. Ligand-specific differences in membrane trafficking of the GLP-1R influence its signalling properties and therapeutic potential in type...
26.
Dai N, Correa Jr I
Methods Mol Biol
. 2020 Aug;
2198:67-78.
PMID: 32822023
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is a widely used technique in the global analysis of epigenetic DNA modifications. The high-resolution chromatographic separation along with sensitive MS detection permits the identification...
27.
Fang Z, Chen S, Pickford P, Broichhagen J, Hodson D, Correa Jr I, et al.
ACS Pharmacol Transl Sci
. 2020 Apr;
3(2):345-360.
PMID: 32296773
Signal bias and membrane trafficking have recently emerged as important considerations in the therapeutic targeting of the glucagon-like peptide-1 receptor (GLP-1R) in type 2 diabetes and obesity. In the present...
28.
Woodcock C, Yu D, Hajian T, Li J, Huang Y, Dai N, et al.
Cell Discov
. 2019 Dec;
5:63.
PMID: 31885874
No abstract available.
29.
Abakir A, Giles T, Cristini A, Foster J, Dai N, Starczak M, et al.
Nat Genet
. 2019 Dec;
52(1):48-55.
PMID: 31844323
R-loops are nucleic acid structures formed by an RNA:DNA hybrid and unpaired single-stranded DNA that represent a source of genomic instability in mammalian cells. Here we show that N-methyladenosine (mA)...
30.
Maffei M, Morelli C, Graham E, Patriarca S, Donzelli L, Doleschall B, et al.
Sci Rep
. 2019 Dec;
9(1):19214.
PMID: 31844114
Gene delivery using vector or viral-based methods is often limited by technical and safety barriers. A promising alternative that circumvents these shortcomings is the direct delivery of proteins into cells....