Ivan R Correa Jr
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Explore the profile of Ivan R Correa Jr including associated specialties, affiliations and a list of published articles.
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77
Citations
2407
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Recent Articles
11.
Chan S, Whipple J, Dai N, Kelley T, Withers K, Tzertzinis G, et al.
RNA
. 2022 Jun;
28(8):1144-1155.
PMID: 35680168
Advances in mRNA synthesis and lipid nanoparticles technologies have helped make mRNA therapeutics and vaccines a reality. The 5' cap structure is a crucial modification required to functionalize synthetic mRNA...
12.
Beasley S, Vandewalle A, Singha M, Nguyen K, England W, Tarapore E, et al.
J Am Chem Soc
. 2022 Apr;
144(16):7085-7088.
PMID: 35416650
Tissues and organs are composed of many diverse cell types, making cell-specific gene expression profiling a major challenge. Herein we report that endogenous enzymes, unique to a cell of interest,...
13.
Yu D, Dai N, Wolf E, Correa Jr I, Zhou J, Wu T, et al.
J Biol Chem
. 2022 Feb;
298(4):101751.
PMID: 35189146
The phosphorylated RNA polymerase II CTD interacting factor 1 (PCIF1) is a methyltransferase that adds a methyl group to the N6-position of 2'O-methyladenosine (A), generating N6, 2'O-dimethyladenosine (mA) when A...
14.
Qi S, Mota J, Chan S, Villarreal J, Dai N, Arya S, et al.
Elife
. 2022 Jan;
11.
PMID: 35060905
Methyltransferase like-3 (METTL3) and METTL14 complex transfers a methyl group from -adenosyl-L-methionine to amino group of adenosine bases in RNA (mA) and DNA (mdA). Emerging evidence highlights a role of...
15.
Yang W, Lin Y, Johnson W, Dai N, Vaisvila R, Weigele P, et al.
Elife
. 2021 Nov;
10.
PMID: 34747693
Shotgun metagenomic sequencing is a powerful approach to study microbiomes in an unbiased manner and of increasing relevance for identifying novel enzymatic functions. However, the potential of metagenomics to relate...
16.
Mulroney L, Wulf M, Schildkraut I, Tzertzinis G, Buswell J, Jain M, et al.
RNA
. 2021 Nov;
28(2):162-176.
PMID: 34728536
Nanopore sequencing devices read individual RNA strands directly. This facilitates identification of exon linkages and nucleotide modifications; however, using conventional direct RNA nanopore sequencing, the 5' and 3' ends of...
17.
Grunberg S, Wolf E, Jin J, Ganatra M, Becker K, Ruse C, et al.
Protein Expr Purif
. 2021 Oct;
190:105987.
PMID: 34637916
Combinations of ribonucleases (RNases) are commonly used to digest RNA into oligoribonucleotide fragments prior to liquid chromatography-mass spectrometry (LC-MS) analysis. The distribution of the RNase target sequences or nucleobase sites...
18.
Murray I, Luyten Y, Fomenkov A, Dai N, Correa Jr I, Farmerie W, et al.
PLoS One
. 2021 Jul;
16(7):e0253267.
PMID: 34228724
We report a new subgroup of Type III Restriction-Modification systems that use m4C methylation for host protection. Recognition specificities for six such systems, each recognizing a novel motif, have been...
19.
Burke E, Rodda S, Lund S, Sun Z, Zeroka M, OToole K, et al.
Proc Natl Acad Sci U S A
. 2021 Jun;
118(26).
PMID: 34155108
TET/JBP (ten-eleven translocation/base J binding protein) enzymes are iron(II)- and 2-oxo-glutarate-dependent dioxygenases that are found in all kingdoms of life and oxidize 5-methylpyrimidines on the polynucleotide level. Despite their prevalence,...
20.
Vaisvila R, Ponnaluri V, Sun Z, Langhorst B, Saleh L, Guan S, et al.
Genome Res
. 2021 Jun;
31(7):1280-1289.
PMID: 34140313
Bisulfite sequencing detects 5mC and 5hmC at single-base resolution. However, bisulfite treatment damages DNA, which results in fragmentation, DNA loss, and biased sequencing data. To overcome these problems, enzymatic methyl-seq...