Ivan Butula
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Explore the profile of Ivan Butula including associated specialties, affiliations and a list of published articles.
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6
Citations
17
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Recent Articles
1.
Kos I, Jadrijevic-Mladar M, Butula I, Birus M, Maravic-Vlahovicek G, Dabelic S
Acta Pharm
. 2013 Jul;
63(2):175-91.
PMID: 23846141
5 Synthesis and biological evaluation of a series (N = 16) of cyclic and acyclic hydroxyurea derivatives, including benzotriazole-, isocyanuric acid- and biuret-containing compounds, are disclosed. 1-N-(benzyloxycarbamoyl)benzotriazole was used as...
2.
Rajic Z, Koncic M, Miloloza K, Perkovic I, Butula I, Bucar F, et al.
Acta Pharm
. 2010 Dec;
60(3):325-37.
PMID: 21134866
Novel primaquine conjugates with non-steroidal anti-inlammatory drugs (PQ-NSAIDs, 4a-h) were prepared, fully chemically characterized and screened for radical scavenging and antioxidant activities. The synthetic procedure leading to twin drugs 4a-h...
3.
Rajic Z, Perkovic I, Butula I, Zorc B, Hadjipavlou-Litina D, Pontiki E, et al.
J Enzyme Inhib Med Chem
. 2009 Sep;
24(5):1179-87.
PMID: 19772490
This paper reports the synthesis of O-methyl and O-ethyl NSAID hydroxamic acids, their antimicrobial activities, and their ability to inhibit urease and soybean lipoxygenase activities. Ibuprofen and fenoprofen hydroxamic acids...
4.
Rajic Z, Butula I, Zorc B, Kraljevic Pavelic S, Hock K, Pavelic K, et al.
Chem Biol Drug Des
. 2009 Feb;
73(3):328-38.
PMID: 19207469
Non-steroidal anti-inflammatory drugs (NSAID) pharmacophores are interesting in designing potential anticancer drugs. Indeed, numerous experimental, epidemiologic and clinical studies suggest that NSAIDs are promising anticancer drugs. Herein, NSAID hydroxamic acids...
5.
Perkovic I, Butula I, Zorc B, Hock K, Kraljevic Pavelic S, Pavelic K, et al.
Chem Biol Drug Des
. 2008 Apr;
71(6):546-53.
PMID: 18410308
The novel hydroxyurea derivatives of l- and d-amino acid amides 5a-l were prepared by aminolysis of N-(1-benzotriazolecarbonyl)-amino acid amides 4a-f with O-benzylhydroxylamine and N-methylhydroxylamine and evaluated for their antiviral and...
6.
Pepeljnjak S, Zorc B, Butula I
Acta Pharm
. 2005 Dec;
55(4):401-8.
PMID: 16375829
Several hydroxamic acids, viz., N-benzyl-N'-hydroxysuccinamide (BHS), poly[alpha,beta-(N-hydroxy)-DL-aspartamide] (PHA), poly[alpha,beta-(N-hydroxy-N-methyl-DL-aspartamide)] (PMHA) and poly[alpha,beta-(N-hydroxy)-DL- aspartamide]/poly[alpha,beta-(N-2-hydroxyethyl)-DL-aspartamide] (PHA-PHEA 1:1) were prepared and screened for their antimicrobial activity. Ten Gram-positive and 7 Gram-negative species of...