Isabelle N King
Overview
Explore the profile of Isabelle N King including associated specialties, affiliations and a list of published articles.
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12
Citations
1414
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Recent Articles
1.
Tran Q, Dieu-Hien H, King I, Sheehan K, Iglowitz M, Periyakoil V
J Pain Symptom Manage
. 2019 Mar;
58(2):344-354.
PMID: 30922704
Vietnamese Americans are a heterogeneous population with a rich, shared experience and historical and cultural influences from Asia and Europe. Societal upheaval resulting from the Vietnam War and varied immigration...
2.
Zhu J, Heidersbach A, Kathiriya I, Garay B, Ivey K, Srivastava D, et al.
Development
. 2017 Mar;
144(5):866-875.
PMID: 28246214
is a small noncoding RNA molecule that modulates gene expression in heart and skeletal muscle. Loss of produces defects in somatic muscle and embryonic heart development, which have been partly...
3.
King I, Yartseva V, Salas D, Kumar A, Heidersbach A, Ando D, et al.
J Biol Chem
. 2014 Apr;
289(20):14263-71.
PMID: 24719334
MicroRNA (miRNA) maturation is regulated by interaction of particular miRNA precursors with specific RNA-binding proteins. Following their biogenesis, mature miRNAs are incorporated into the RNA-induced silencing complex (RISC) where they...
4.
Kwon C, Cheng P, King I, Andersen P, Shenje L, Nigam V, et al.
Nat Cell Biol
. 2011 Aug;
13(10):1244-51.
PMID: 21841793
Cellular decisions of self-renewal or differentiation arise from integration and reciprocal titration of numerous regulatory networks. Notch and Wnt/β-catenin signalling often intersect in stem and progenitor cells and regulate each...
5.
Qian L, Wythe J, Liu J, Cartry J, Vogler G, Mohapatra B, et al.
J Cell Biol
. 2011 Jun;
193(7):1181-96.
PMID: 21690310
Unraveling the gene regulatory networks that govern development and function of the mammalian heart is critical for the rational design of therapeutic interventions in human heart disease. Using the Drosophila...
6.
King I, Qian L, Liang J, Huang Y, Shieh J, Kwon C, et al.
Dev Cell
. 2011 Apr;
20(4):497-510.
PMID: 21497762
Many molecular pathways involved in heart disease have their roots in evolutionarily ancient developmental programs that depend critically on gene dosage and timing. MicroRNAs (miRNAs) modulate gene dosage posttranscriptionally, and...
7.
Ransom J, King I, Garg V, Srivastava D
J Biol Chem
. 2008 Oct;
283(51):35845-52.
PMID: 18852265
Myocardin (MYOCD) is a transcriptional co-activator that promotes cardiac or smooth muscle gene programs through its interaction with myocyte-enhancing factor (MEF2) or serum-response factor (SRF). Isoforms of MYOCD with a...
8.
Jia H, King I, Chopra S, Wan H, Ni T, Jiang C, et al.
Proc Natl Acad Sci U S A
. 2007 Aug;
104(35):14008-13.
PMID: 17715064
Embryonic organs attain their final dimensions through the generation of proper cell number and size, but the control mechanisms remain obscure. Here, we establish Gridlock (Grl), a Hairy-related basic helix-loop-helix...
9.
King I, Kathiriya I, Murakami M, Nakagawa M, Gardner K, Srivastava D, et al.
Biochem Biophys Res Commun
. 2006 May;
345(1):446-52.
PMID: 16682003
Notch signaling is central to cell differentiation, organ development, and apoptosis. Upon ligand binding, the Notch intracellular domain (NotchIC) translocates to the nucleus to interact with its DNA-binding partner, RBP-Jkappa....
10.
Garg V, Muth A, Ransom J, Schluterman M, Barnes R, King I, et al.
Nature
. 2005 Jul;
437(7056):270-4.
PMID: 16025100
Calcification of the aortic valve is the third leading cause of heart disease in adults. The incidence increases with age, and it is often associated with a bicuspid aortic valve...