Irfan S Kathiriya
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Explore the profile of Irfan S Kathiriya including associated specialties, affiliations and a list of published articles.
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16
Citations
1009
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Recent Articles
1.
Grant Z, Kuang S, Zhang S, Horrillo A, Rao K, Kameswaran V, et al.
bioRxiv
. 2025 Jan;
PMID: 39829922
Dosage-sensitive transcription factors (TFs) underlie altered gene regulation in human developmental disorders, and cell-type specific gene regulation is linked to the reorganization of 3D chromatin during cellular differentiation. Here, we...
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Morell E, Colglazier E, Becerra J, Stevens L, Steurer M, Sharma A, et al.
Pulm Circ
. 2024 Apr;
14(2):e12360.
PMID: 38618291
Cardiac catheterization remains the gold standard for the diagnosis and management of pediatric pulmonary hypertension (PH). There is lack of consensus regarding optimal anesthetic and airway regimen. This retrospective study...
4.
Kathiriya I, Dominguez M, Rao K, Muncie-Vasic J, Devine W, Hu K, et al.
bioRxiv
. 2024 Feb;
PMID: 38370632
Failure of septation of the interventricular septum (IVS) is the most common congenital heart defect (CHD), but mechanisms for patterning the IVS are largely unknown. We show that a progenitor...
5.
Blair A, Hu R, Farah E, Chi N, Pollard K, Przytycki P, et al.
Bioinform Adv
. 2022 Aug;
2(1):vbac051.
PMID: 35967929
Motivation: Unsupervised clustering of single-cell transcriptomics is a powerful method for identifying cell populations. Static visualization techniques for single-cell clustering only display results for a single resolution parameter. Analysts will...
6.
Hota S, Rao K, Blair A, Khalilimeybodi A, Hu K, Thomas R, et al.
Nature
. 2022 Jan;
602(7895):129-134.
PMID: 35082446
Differentiation proceeds along a continuum of increasingly fate-restricted intermediates, referred to as canalization. Canalization is essential for stabilizing cell fate, but the mechanisms that underlie robust canalization are unclear. Here...
7.
Jung M, Libaw J, Manuel S, Kathiriya I, Srejic U, Gandhi S
J Clin Anesth
. 2021 Feb;
70:110192.
PMID: 33556792
Study Objective: Anesthesiologists have a high prevalence of burnout with adverse effects on professionalism and safety. The objective of this study was to assess the impact of an interactive anesthesiology...
8.
Kathiriya I, Rao K, Iacono G, Devine W, Blair A, Hota S, et al.
Dev Cell
. 2020 Dec;
56(3):292-309.e9.
PMID: 33321106
Haploinsufficiency of transcriptional regulators causes human congenital heart disease (CHD); however, the underlying CHD gene regulatory network (GRN) imbalances are unknown. Here, we define transcriptional consequences of reduced dosage of...
9.
George M, Duan Q, Nagle A, Kathiriya I, Huang Y, Rao K, et al.
Development
. 2019 Dec;
146(23).
PMID: 31784461
Long intergenic non-coding RNAs (lincRNAs) have been implicated in gene regulation, but their requirement for development needs empirical interrogation. We computationally identified nine murine lincRNAs that have developmentally regulated transcriptional...
10.
Zhu J, Heidersbach A, Kathiriya I, Garay B, Ivey K, Srivastava D, et al.
Development
. 2017 Mar;
144(5):866-875.
PMID: 28246214
is a small noncoding RNA molecule that modulates gene expression in heart and skeletal muscle. Loss of produces defects in somatic muscle and embryonic heart development, which have been partly...