Isabelle Marois
Overview
Explore the profile of Isabelle Marois including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
170
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Recent Articles
1.
Dubois J, Bonnell E, Filion A, Frion J, Zimmer S, Khan M, et al.
Proc Natl Acad Sci U S A
. 2025 Jan;
122(2):e2419712122.
PMID: 39772744
To achieve replicative immortality, cancer cells must activate telomere maintenance mechanisms. In 10 to 15% of cancers, this is enabled by recombination-based alternative lengthening of telomeres pathways (ALT). ALT cells...
2.
Kochman R, Ba I, Yates M, Pirabakaran V, Gourmelon F, Churikov D, et al.
Genes Dev
. 2024 Sep;
38(15-16):755-771.
PMID: 39231615
Premature telomere shortening or telomere instability is associated with a group of rare and heterogeneous diseases collectively known as telomere biology disorders (TBDs). Here we identified two unrelated individuals with...
3.
Djerir B, Marois I, Dubois J, Findlay S, Morin T, Senoussi I, et al.
J Biol Chem
. 2024 Jul;
300(8):107545.
PMID: 38992439
DNA double-strand breaks (DSBs) elicit an elaborate response to signal damage and trigger repair via two major pathways: nonhomologous end-joining (NHEJ), which functions throughout the interphase, and homologous recombination (HR),...
4.
Yates M, Marois I, St-Hilaire E, Ronato D, Djerir B, Brochu C, et al.
PLoS Biol
. 2024 Mar;
22(3):e3002552.
PMID: 38502677
Impediments in replication fork progression cause genomic instability, mutagenesis, and severe pathologies. At stalled forks, RPA-coated single-stranded DNA (ssDNA) activates the ATR kinase and directs fork remodeling, 2 key early...
5.
Colombo E, Desilets A, Hassanzadeh M, Lemieux G, Marois I, Cliche D, et al.
ChemMedChem
. 2023 Oct;
19(2):e202300458.
PMID: 37864572
Human influenza viruses cause acute respiratory symptoms that can lead to death. Due to the emergence of antiviral drug-resistant strains, there is an urgent requirement for novel antiviral agents and...
6.
Simard O, Leduc F, Acteau G, Arguin M, Gregoire M, Brazeau M, et al.
J Vis Exp
. 2016 Jan;
(106):e53379.
PMID: 26780208
The differentiation of mouse spermatids is one critical process for the production of a functional male gamete with an intact genome to be transmitted to the next generation. So far,...
7.
Meunier I, Morisseau O, Garneau E, Marois I, Cloutier A, Richter M
PLoS One
. 2015 Sep;
10(9):e0138055.
PMID: 26381265
Despite a relatively low fatality rate, the 2009 H1N1 pandemic virus differed from other seasonal viruses in that it caused mortality and severe pneumonia in the young and middle-aged population...
8.
Marois I, Cloutier A, Garneau E, Lesur O, Richter M
FASEB J
. 2014 Nov;
29(3):973-87.
PMID: 25414485
The clinical benefits of oseltamivir (Tamiflu) are well established, but the effects of antiviral treatment on the immune response are poorly understood. By use of flow cytometric analyses and the...
9.
Marois I, Cloutier A, Meunier I, Weingartl H, Cantin A, Richter M
PLoS One
. 2014 Oct;
9(10):e110631.
PMID: 25333287
Antivirals that are currently used to treat influenza virus infections target components of the virus which can mutate rapidly. Consequently, there has been an increase in the number of resistant...
10.
Simard O, Gregoire M, Arguin M, Brazeau M, Leduc F, Marois I, et al.
Hum Mutat
. 2014 Aug;
35(11):1280-4.
PMID: 25136821
Transient DNA breaks and evidence of DNA damage response have recently been reported during the chromatin remodeling process in haploid spermatids, creating a potential window of enhanced genetic instability. We...