Isabelle Ader
Overview
Explore the profile of Isabelle Ader including associated specialties, affiliations and a list of published articles.
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30
Citations
641
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Recent Articles
1.
Pey V, Doumard E, Komorowski M, Rouget A, Delmas C, Vardon-Bounes F, et al.
Digit Health
. 2024 Apr;
10:20552076241234746.
PMID: 38628633
Background: Out-of-hospital cardiac arrest (OHCA) represents a major burden for society and health care, with an average incidence in adults of 67 to 170 cases per 100,000 person-years in Europe...
2.
Tremblay-Franco M, Canlet C, Carriere A, Nakhle J, Galinier A, Portais J, et al.
J Gerontol A Biol Sci Med Sci
. 2024 Mar;
79(5).
PMID: 38452244
Alzheimer's disease is strongly linked to metabolic abnormalities. We aimed to distinguish amyloid-positive people who progressed to cognitive decline from those who remained cognitively intact. We performed untargeted metabolomics of...
3.
Farge T, Nakhle J, Lagarde D, Cognet G, Polley N, Castellano R, et al.
Cancer Res
. 2023 Jun;
83(17):2824-2838.
PMID: 37327406
Significance: CD36 promotes blast migration and extramedullary disease in acute myeloid leukemia and represents a critical target that can be exploited for clinical prognosis and patient treatment.
4.
Bernard D, Doumard E, Ader I, Kemoun P, Pages J, Galinier A, et al.
Aging Cell
. 2023 Jun;
22(8):e13872.
PMID: 37300327
Attaining personalized healthy aging requires accurate monitoring of physiological changes and identifying subclinical markers that predict accelerated or delayed aging. Classic biostatistical methods most rely on supervised variables to estimate...
5.
Godet A, Roussel E, David F, Hantelys F, Morfoisse F, Alves J, et al.
Elife
. 2022 Dec;
11.
PMID: 36546462
Internal ribosome entry sites (IRESs) drive translation initiation during stress. In response to hypoxia, (lymph)angiogenic factors responsible for tissue revascularization in ischemic diseases are induced by the IRES-dependent mechanism. Here,...
6.
Sanchez-Sanchez J, Ader I, Jeanson Y, Planat-Benard V, Vellas B, Casteilla L, et al.
J Gerontol A Biol Sci Med Sci
. 2022 Nov;
78(3):424-432.
PMID: 36373873
Periostin, involved in extracellular matrix development and support, has been shown to be elevated in senescent tissues and fibrotic states, transversal signatures of aging. We aimed to explore associations between...
7.
Lagarde D, Jeanson Y, Portais J, Galinier A, Ader I, Casteilla L, et al.
Front Physiol
. 2021 Jul;
12:689747.
PMID: 34276410
Lactate, a metabolite produced when the glycolytic flux exceeds mitochondrial oxidative capacities, is now viewed as a critical regulator of metabolism by acting as both a carbon and electron carrier...
8.
Lagarde D, Jeanson Y, Barreau C, Moro C, Peyriga L, Cahoreau E, et al.
J Biol Chem
. 2020 Dec;
296:100137.
PMID: 33268383
Activation of energy-dissipating brown/beige adipocytes represents an attractive therapeutic strategy against metabolic disorders. While lactate is known to induce beiging through the regulation of Ucp1 gene expression, the role of...
9.
Carriere A, Lagarde D, Jeanson Y, Portais J, Galinier A, Ader I, et al.
J Physiol Biochem
. 2020 Jan;
76(2):241-250.
PMID: 31898016
Thermogenic (brown and beige) adipose tissues improve glucose and lipid homeostasis and therefore represent putative targets to cure obesity and related metabolic diseases including type II diabetes. Beside decades of...
10.
Hantelys F, Godet A, David F, Tatin F, Renaud-Gabardos E, Pujol F, et al.
Elife
. 2019 Dec;
8.
PMID: 31815666
Hypoxia, a major inducer of angiogenesis, triggers major changes in gene expression at the transcriptional level. Furthermore, under hypoxia, global protein synthesis is blocked while internal ribosome entry sites (IRES)...