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Olivier Cuvillier

Explore the profile of Olivier Cuvillier including associated specialties, affiliations and a list of published articles. Areas
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Articles 61
Citations 1523
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Recent Articles
1.
Beaurain M, Talmont F, Pierre D, Peran P, Boucher S, Hitzel A, et al.
Mol Imaging Biol . 2023 Mar; 25(4):692-703. PMID: 36944798
Purpose: NMDA receptors (NMDARs) dysfunction plays a central role in the physiopathology of psychiatric and neurodegenerative disorders whose mechanisms are still poorly understood. The development of a PET (positron emission...
2.
Wang X, Zhang C, Madji R, Voros C, Mazeres S, Bijani C, et al.
Molecules . 2023 Jan; 28(2). PMID: 36677751
A series of seven novel iridium complexes were synthetized and characterized as potential photosensitizers for photodynamic therapy (PDT) applications. Among them, four complexes were evaluated in vitro for their anti-proliferative...
3.
Talmont F, Mitri E, Dozier C, Besson A, Cuvillier O, Hatzoglou A
Cancers (Basel) . 2022 Apr; 14(7). PMID: 35406433
Sphingosine 1-phosphate (S1P), a bioactive lipid, interacts with five widely expressed G protein-coupled receptors (S1P1-5), regulating a variety of downstream signaling pathways with overlapping but also opposing functions. To date,...
4.
Gomez-Brouchet A, Illac C, Ledoux A, Fortin P, De Barros S, Vabre C, et al.
Cancers (Basel) . 2022 Feb; 14(3). PMID: 35158767
The Sphingosine kinase-1/Sphingosine 1-Phosphate (SphK1/S1P) signaling pathway is overexpressed in various cancers, and is instrumental for the adaptation to hypoxia in a number of solid tumor models, but no data...
5.
Borel M, Cuvillier O, Magne D, Mebarek S, Brizuela L
Mol Cell Biochem . 2020 Jul; 473(1-2):263-279. PMID: 32661773
Prostate cancer (PCa) is the most frequent cancer among men and the first cause of death over 65. Approximately 90% of patients with advanced disease will develop bone metastasis, which...
6.
Zhang C, Fortin P, Barnoin G, Qin X, Wang X, Fernandez Alvarez A, et al.
Angew Chem Int Ed Engl . 2020 Apr; 59(29):12062-12068. PMID: 32304346
A family of hybrid complexes combining two biologically active motifs, an artemisinin derivative and a cationic bis(NHC)-gold(I) unit, has been synthesized. One of these complexes, 2 a, has been analyzed...
7.
Talmont F, Hatzoglou A, Cuvillier O
Med Sci (Paris) . 2020 Apr; 36(3):243-252. PMID: 32228843
Multiple sclerosis (MS) is a disease of the central nervous system with a very debilitating inflammatory component that usually affects young people (years 20-40). This disease is characterized by the...
8.
El Jamal A, Bougault C, Mebarek S, Magne D, Cuvillier O, Brizuela L
Bone . 2019 Oct; 130:115087. PMID: 31648078
Sphingolipids display important functions in various pathologies such as cancer, obesity, diabetes, cardiovascular or neurodegenerative diseases. Sphingosine, sphingosine 1-phosphate (S1P), and ceramide are the central molecules of sphingolipid metabolism. Sphingosine...
9.
Gachechiladze M, Tichy T, Kolek V, Grygarkova I, Klein J, Mgebrishvili G, et al.
Oncol Lett . 2019 Aug; 18(2):1259-1266. PMID: 31423186
Sphingosine 1-phosphate (S1P) is a bioactive lipid metabolite associated with cancer cell proliferation, survival, migration and regulation of tumor angiogenesis in various cellular and animal models. Sphingosine kinase-1 (SphK1) and...
10.
Talmont F, Mouledous L, Baranger M, Gomez-Brouchet A, Zajac J, Deffaud C, et al.
PLoS One . 2019 Mar; 14(3):e0213203. PMID: 30845158
Although sphingosine-1-phosphate receptor 1 (S1P1) has been shown to trigger several S1P targeted functions such as immune cell trafficking, cell proliferation, migration, or angiogenesis, tools that allow the accurate detection...