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Isabel Carrascoso

Explore the profile of Isabel Carrascoso including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 206
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Recent Articles
1.
Carrascoso I, Velasco B, Izquierdo J
Int J Mol Sci . 2021 Dec; 22(23). PMID: 34884582
T-cell intracellular antigen 1 (TIA1) is a multifunctional RNA-binding protein involved in regulating gene expression and splicing during development and in response to environmental stress, to maintain cell homeostasis and...
2.
Carrascoso I, Alcalde J, Tabas-Madrid D, Oliveros J, Izquierdo J
PLoS One . 2018 Dec; 13(12):e0208526. PMID: 30533021
Control of gene expression depends on genetics and environmental factors. The T-cell intracellular antigens T-cell intracellular antigen 1 (TIA1), TIA1-like/related protein (TIAL1/TIAR) and human antigen R (HuR/ELAVL1) are RNA-binding proteins...
3.
Carrascoso I, Sanchez-Jimenez C, Silion E, Alcalde J, Izquierdo J
Mol Cell Biol . 2018 Oct; 39(1). PMID: 30348840
Welander distal myopathy (WDM) is a muscle dystrophy characterized by adult-onset distal muscle weakness, prevalently impacting the distal long extensors of the hands and feet. WDM is an autosomal dominant...
4.
Acin-Perez R, Lechuga-Vieco A, Munoz M, Nieto-Arellano R, Torroja C, Sanchez-Cabo F, et al.
Sci Transl Med . 2018 Mar; 10(434). PMID: 29593106
Heart failure (HF) is a major health and economic burden in developed countries. It has been proposed that the pathogenesis of HF may involve the action of mitochondria. We evaluate...
5.
Carrascoso I, Alcalde J, Sanchez-Jimenez C, Gonzalez-Sanchez P, Izquierdo J
Mol Cell Biol . 2017 Jun; 37(17). PMID: 28630277
Mitochondria undergo frequent morphological changes to control their function. We show here that T-cell intracellular antigens (TIA1b/TIARb) and Hu antigen R (HuR) have antagonistic roles in mitochondrial function by modulating...
6.
Carrascoso I, Sanchez-Jimenez C, Izquierdo J
Biochem J . 2014 Jun; 461(1):43-50. PMID: 24927121
TIA (T-cell intracellular antigens)-knockdown HeLa cells show an increase in ribosomes and translational machinery components. This increase correlates with specific changes in translationally up-regulated mRNAs involved in cell-cycle progression and...
7.
Acin-Perez R, Carrascoso I, Baixauli F, Roche-Molina M, Latorre-Pellicer A, Fernandez-Silva P, et al.
Cell Metab . 2014 May; 19(6):1020-33. PMID: 24856931
Electron flux in the mitochondrial electron transport chain is determined by the superassembly of mitochondrial respiratory complexes. Different superassemblies are dedicated to receive electrons derived from NADH or FADH2, allowing...
8.
Carrascoso I, Sanchez-Jimenez C, Izquierdo J
Mol Cancer . 2014 Apr; 13:90. PMID: 24766723
Background: The permanent down-regulated expression of T-cell intracellular antigen (TIA) proteins in HeLa cells improves cytoskeleton-mediated functions such as cell proliferation and tumor growth. Methods: Making use of human and...
9.
Sanchez-Jimenez C, Carrascoso I, Barrero J, Izquierdo J
BMC Mol Biol . 2013 Feb; 14:4. PMID: 23387986
Background: T-cell intracellular antigen (TIA) proteins function as regulators of cell homeostasis. These proteins control gene expression globally at multiple levels in response to dynamic regulatory changes and environmental stresses....
10.
Izquierdo J, Alcalde J, Carrascoso I, Reyes R, Ludena M
Biochem J . 2011 Feb; 435(2):337-44. PMID: 21284605
TIA (T-cell intracellular antigen) proteins function as DNA/RNA trans-acting regulators to expand transcriptome and proteome diversity in mammals. In the present paper we report that the stable silencing of TIA1...