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Isaac T Yonemoto

Explore the profile of Isaac T Yonemoto including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 217
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Recent Articles
1.
Yonemoto I, Weyman P
Methods Mol Biol . 2016 Oct; 1498:359-366. PMID: 27709588
Site-directed mutagenesis is a commonly used molecular biology technique to manipulate biological sequences, and is especially useful for studying sequence determinants of enzyme function or designing proteins with improved activity....
2.
Yonemoto I, Smith H, Weyman P
Int J Mol Sci . 2015 Jan; 16(1):2020-33. PMID: 25603181
Photobiological hydrogen production is an attractive, carbon-neutral means to convert solar energy to hydrogen. We build on previous research improving the Alteromonas macleodii "Deep Ecotype" [NiFe] hydrogenase, and report progress...
3.
Yonemoto I, Clarkson B, Smith H, Weyman P
BMC Biochem . 2014 Jun; 15:10. PMID: 24934472
Background: In order to understand the effects of FeS cluster attachment in [NiFe] hydrogenase, we undertook a study to substitute all 12 amino acid positions normally ligating the three FeS...
4.
Karas B, Molparia B, Jablanovic J, Hermann W, Lin Y, Dupont C, et al.
J Biol Eng . 2013 Dec; 7(1):30. PMID: 24325901
Background: Synthetic genomic approaches offer unique opportunities to use powerful yeast and Escherichia coli genetic systems to assemble and modify chromosome-sized molecules before returning the modified DNA to the target...
5.
Yonemoto I, Matteri C, Nguyen T, Smith H, Weyman P
J Biol Eng . 2013 Jul; 7(1):17. PMID: 23819621
Background: Photosynthetic microorganisms that directly channel solar energy to the production of molecular hydrogen are a potential future biofuel system. Building such a system requires installation of a hydrogenase in...
6.
Noskov V, Karas B, Young L, Chuang R, Gibson D, Lin Y, et al.
ACS Synth Biol . 2013 May; 1(7):267-73. PMID: 23651249
The ability to assemble large pieces of prokaryotic DNA by yeast recombination has great application in synthetic biology, but cloning large pieces of high G+C prokaryotic DNA in yeast can...
7.
Karas B, Tagwerker C, Yonemoto I, Hutchison 3rd C, Smith H
ACS Synth Biol . 2013 May; 1(1):22-8. PMID: 23651007
Cloning of whole genomes of the genus Mycoplasma in yeast has been an essential step for the creation of the first synthetic cell. The genome of the synthetic cell is...
8.
Yonemoto I, Li W, Khullar A, Reixach N, Gerratana B
ACS Chem Biol . 2012 Mar; 7(6):973-7. PMID: 22390171
Pursuit of the actinomycete pyrrolobenzodiazepine natural product sibiromycin as a chemotherapeutic agent has been limited by its cardiotoxicity. Among pyrrolobenzodiazepines, cardiotoxicity is associated with hydroxylation at position 9. Deletion of...
9.
Antonczak A, Simova Z, Yonemoto I, Bochtler M, Piasecka A, Czapinska H, et al.
Proc Natl Acad Sci U S A . 2011 Jan; 108(4):1320-5. PMID: 21224416
The site-selective encoding of noncanonical amino acids (NAAs) is a powerful technique for the installation of novel chemical functional groups in proteins. This is often achieved by recoding a stop...
10.
Yonemoto I, Tippmann E
Bioessays . 2010 Mar; 32(4):314-21. PMID: 20217843
No abstract available.