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Philip D Weyman

Explore the profile of Philip D Weyman including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 518
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Recent Articles
1.
Garza E, Bielinski V, Espinoza J, Orlandi K, Alfaro J, Bolt T, et al.
ACS Synth Biol . 2023 Oct; 12(11):3215-3228. PMID: 37857380
While diatoms are promising synthetic biology platforms, there currently exists a limited number of validated genetic regulatory parts available for genetic engineering. The standard method for diatom transformation, nonspecific introduction...
2.
Stuart R, Pederson E, Weyman P, Weber P, Rassmussen U, Dupont C
ISME J . 2020 Aug; 14(12):3068-3078. PMID: 32814866
In nitrogen-limited boreal forests, associations between feathermoss and diazotrophic cyanobacteria control nitrogen inputs and thus carbon cycling, but little is known about the molecular regulators required for initiation and maintenance...
3.
Khilko Y, Weyman P, Glass J, Adams M, McNeil M, Griffin P
BMC Biotechnol . 2018 Jun; 18(1):37. PMID: 29859085
Background: Custom synthesized DNA is in high demand for synthetic biology applications. However, current technologies to produce these sequences using assembly from DNA oligonucleotides are costly and labor-intensive. The automation...
4.
Mariscal A, Kakizawa S, Hsu J, Tanaka K, Gonzalez-Gonzalez L, Broto A, et al.
ACS Synth Biol . 2018 May; 7(6):1538-1552. PMID: 29786424
Functional genomics studies in minimal mycoplasma cells enable unobstructed access to some of the most fundamental processes in biology. Conventional transposon bombardment and gene knockout approaches often fail to reveal...
5.
Warshan D, Liaimer A, Pederson E, Kim S, Shapiro N, Woyke T, et al.
Mol Biol Evol . 2018 Mar; 35(5):1160-1175. PMID: 29554291
Cyanobacteria belonging to the genus Nostoc comprise free-living strains and also facultative plant symbionts. Symbiotic strains can enter into symbiosis with taxonomically diverse range of host plants. Little is known...
6.
Warshan D, Espinoza J, Stuart R, Richter R, Kim S, Shapiro N, et al.
ISME J . 2017 Aug; 11(12):2821-2833. PMID: 28800136
Dinitrogen (N)-fixation by cyanobacteria in symbiosis with feathermosses is the primary pathway of biological nitrogen (N) input into boreal forests. Despite its significance, little is known about the cyanobacterial gene...
7.
Diner R, Noddings C, Lian N, Kang A, McQuaid J, Jablanovic J, et al.
Proc Natl Acad Sci U S A . 2017 Jul; 114(29):E6015-E6024. PMID: 28673987
Centromeres are essential for cell division and growth in all eukaryotes, and knowledge of their sequence and structure guides the development of artificial chromosomes for functional cellular biology studies. Centromeric...
8.
Yonemoto I, Weyman P
Methods Mol Biol . 2016 Oct; 1498:359-366. PMID: 27709588
Site-directed mutagenesis is a commonly used molecular biology technique to manipulate biological sequences, and is especially useful for studying sequence determinants of enzyme function or designing proteins with improved activity....
9.
Diner R, Bielinski V, Dupont C, Allen A, Weyman P
Front Bioeng Biotechnol . 2016 Aug; 4:65. PMID: 27551676
Conjugation of episomal plasmids from bacteria to diatoms advances diatom genetic manipulation by simplifying transgene delivery and providing a stable and consistent gene expression platform. To reach its full potential,...
10.
Karas B, Diner R, Lefebvre S, McQuaid J, Phillips A, Noddings C, et al.
Nat Commun . 2015 Apr; 6:6925. PMID: 25897682
Eukaryotic microalgae hold great promise for the bioproduction of fuels and higher value chemicals. However, compared with model genetic organisms such as Escherichia coli and Saccharomyces cerevisiae, characterization of the...