Irina Budunova
Overview
Explore the profile of Irina Budunova including associated specialties, affiliations and a list of published articles.
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26
Citations
427
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Recent Articles
1.
Tsoi L, Dong Y, Patrick M, Sarkar M, Zhang H, Bogle R, et al.
Res Sq
. 2025 Feb;
PMID: 39975900
Inflammatory skin diseases (ISDs) exhibit varying prevalence across different ancestry background and geographical regions. Genetic research for complex ISDs has predominantly centered on European Ancestry (EurA) populations and genetic effects...
2.
Vlasova O, Antonova I, Magomedova K, Osipova A, Shtompel P, Borunova A, et al.
Int J Mol Sci
. 2025 Jan;
26(1.
PMID: 39796235
Previously we discovered that among 15 DNA-binding plant secondary metabolites (PSMs) possessing anticancer activity, 11 compounds cause depletion of the chromatin-bound linker histones H1.2 and/or H1.4. Chromatin remodeling or multiH1...
3.
Zhidkova E, Lylova E, Grigoreva D, Kirsanov K, Osipova A, Kulikov E, et al.
Int J Mol Sci
. 2022 Sep;
23(17).
PMID: 36077083
Regulated in Development and DNA Damage Response 1 (REDD1)/DNA Damage-Induced Transcript 4 (DDIT4) is an immediate early response gene activated by different stress conditions, including growth factor depletion, hypoxia, DNA...
4.
Klopot A, Baida G, Kel A, Tsoi L, Perez White B, Budunova I
J Invest Dermatol
. 2021 Nov;
142(5):1360-1371.e15.
PMID: 34757068
Differences in the morphology and physiology of darkly pigmented skin compared with those of lightly pigmented skin are well-recognized. There are also disparities in the prevalence and clinical features for...
5.
Mirzoeva S, Yang Y, Klopot A, Budunova I, Brown M
J Immunol
. 2021 Aug;
207(7):1747-1754.
PMID: 34452931
REDD1 is an energy sensor and stress-induced mTOR inhibitor. Recently, its novel role in linking metabolism and inflammation/immune responses has emerged. In this study, we assessed the role of REDD1...
6.
Junking M, Rattanaburee T, Panya A, Budunova I, Haegeman G, Yenchitsomanus P
Asian Pac J Cancer Prev
. 2020 Sep;
21(9):2673-2681.
PMID: 32986368
Background: Cholangiocarcinoma (CCA) is a fatal cancer with high resistance to anticancer drugs. The development of new drugs or compounds to be used alone or in combination with currently available...
7.
Lesovaya E, Savinkova A, Morozova O, Lylova E, Zhidkova E, Kulikov E, et al.
Mol Cancer Ther
. 2020 Jun;
19(9):1898-1908.
PMID: 32546661
Glucocorticoids are widely used for therapy of hematologic malignancies. Unfortunately, chronic treatment with glucocorticoids commonly leads to adverse effects including skin and muscle atrophy and osteoporosis. We found recently that...
8.
Baida G, Agarwal S, Readhead B, Dudley J, Budunova I
Oncotarget
. 2020 Feb;
11(4):409-418.
PMID: 32064044
Topical glucocorticoids, well-known anti-inflammatory drugs, induce multiple adverse effects, including skin atrophy. The sex-specific effects of systemic glucocorticoids are known, but sexual dimorphism of therapeutic and side effects of topical...
9.
Rivera-Gonzalez G, Klopot A, Sabin K, Baida G, Horsley V, Budunova I
J Invest Dermatol
. 2020 Feb;
140(9):1698-1705.e1.
PMID: 32032578
Dermal white adipose tissue (dWAT) expansion is associated with important homeostatic and pathologic processes in skin. Even though mTOR/protein kinase B signaling is important for adipogenesis, the role of regulated...
10.
Lili L, Klopot A, Readhead B, Baida G, Dudley J, Budunova I
J Invest Dermatol
. 2019 Jun;
139(11):2281-2291.
PMID: 31247200
Glucocorticoids are the most frequently used anti-inflammatory drugs in dermatology. However, the molecular signature of glucocorticoids and their receptor in human skin is largely unknown. Our validated bioinformatics analysis of...