Alexander Yemelyanov
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Explore the profile of Alexander Yemelyanov including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
268
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Recent Articles
1.
Han F, Dellacecca E, Barse L, Cosgrove C, Henning S, Ankney C, et al.
Am J Respir Cell Mol Biol
. 2020 Feb;
62(6):793-804.
PMID: 32078336
Patients with lymphangioleiomyomatosis (LAM) develop pulmonary cysts associated with neoplastic, smooth muscle-like cells that feature neuroendocrine cell markers. The disease preferentially affects premenopausal women. Existing therapeutics do not cure LAM....
2.
Baida G, Bhalla P, Yemelyanov A, Stechschulte L, Shou W, Readhead B, et al.
Oncotarget
. 2018 Nov;
9(78):34772-34783.
PMID: 30410676
FKBP51 (FK506-binding protein 51) is a known co-chaperone and regulator of the glucocorticoid receptor (GR), which usually attenuates its activity. FKBP51 is one of the major GR target genes in...
3.
Lesovaya E, Yemelyanov A, Swart A, Swart P, Haegeman G, Budunova I
Oncotarget
. 2015 Oct;
6(31):30730-44.
PMID: 26436695
Glucocorticoids are among the most effective anti-inflammatory drugs, and are widely used for cancer therapy. Unfortunately, chronic treatment with glucocorticoids results in multiple side effects. Thus, there was an intensive...
4.
Lesovaya E, Yemelyanov A, Kirsanov K, Popa A, Belitsky G, Yakubovskaya M, et al.
Cell Cycle
. 2012 Dec;
12(1):133-44.
PMID: 23255118
Glucocorticoids are widely used for the treatment of hematological malignancies; however, their chronic use results in numerous metabolic side effects. Thus, the development of selective glucocorticoid receptor (GR) activators (SEGRA)...
5.
Mirochnik Y, Veliceasa D, Williams L, Maxwell K, Yemelyanov A, Budunova I, et al.
PLoS One
. 2012 Mar;
7(3):e31052.
PMID: 22403609
The accepted androgen receptor (AR) role is to promote proliferation and survival of prostate epithelium and thus prostate cancer progression. While growth-inhibitory, tumor-suppressive AR effects have also been documented, the...
6.
Yemelyanov A, Bhalla P, Yang X, Ugolkov A, Iwadate K, Karseladze A, et al.
Cell Cycle
. 2012 Jan;
11(2):395-406.
PMID: 22223138
Androgen (AR) and glucocorticoid (GR) receptor signaling play opposing roles in prostate tumorigenesis: in prostate, AR acts as an oncogene, and GR is a tumor suppressor. Recently, we found that...
7.
Yemelyanov A, Czwornog J, Gera L, Joshi S, Chatterton Jr R, Budunova I
Cancer Res
. 2008 Jun;
68(12):4763-73.
PMID: 18559523
Androgen receptor (AR)- and glucocorticoid receptor (GR)- mediated signaling play opposite roles in prostate tumorigenesis: AR promotes prostate carcinoma (PC) development, whereas GR acts as a tumor suppressor. Compound A...
8.
Chebotaev D, Yemelyanov A, Budunova I
Mol Carcinog
. 2007 Jun;
46(8):732-40.
PMID: 17538956
Glucocorticoid hormones exert a tumor suppressor effect in different experimental models, including mouse skin carcinogenesis. The glucocorticoid control of cellular functions is mediated via the glucocorticoid receptor (GR), a well-known...
9.
Nelius T, Filleur S, Yemelyanov A, Budunova I, Shroff E, Mirochnik Y, et al.
Int J Cancer
. 2007 May;
121(5):999-1008.
PMID: 17487836
The androgen role in the maintenance of prostate epithelium is subject to conflicting opinions. While androgen ablation drives the regression of normal and cancerous prostate, testosterone may cause both proliferation...
10.
Billsten H, Bhosale P, Yemelyanov A, Bernstein P, Polivka T
Photochem Photobiol
. 2003 Aug;
78(2):138-45.
PMID: 12945581
The macula of the human retina contains high amounts of the xanthophyll carotenoids lutein and zeaxanthin [a mixture of (3R,3'R)-zeaxanthin and (3R,3'S-meso)-zeaxanthin]. Recently, it was shown that the uptake and...