Irene Lepori
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Explore the profile of Irene Lepori including associated specialties, affiliations and a list of published articles.
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9
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37
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Recent Articles
1.
Lepori I, Liu Z, Evbarunegbe N, Feng S, Brown T, Mane K, et al.
bioRxiv
. 2025 Mar;
PMID: 40060676
Tuberculosis (TB), caused by (Mtb), is the deadliest single-agent infection worldwide. Current antibiotic treatment for TB takes a minimum of four months, underscoring the need for better therapeutics. The unique...
2.
Dash R, Liu Z, Lepori I, Chordia M, Ocius K, Holsinger K, et al.
bioRxiv
. 2025 Jan;
PMID: 39868157
The mycomembrane of mycobacteria has long been regarded as the primary barrier to the accumulation of molecules within these bacteria. Understanding accumulation beyond the mycomembrane of () is crucial for...
3.
Lepori I, Jackson K, Liu Z, Chordia M, Wong M, Rivera S, et al.
bioRxiv
. 2025 Jan;
PMID: 39803531
Abstract Graphic:
4.
Lepori I, Roncetti M, Vitiello M, Barresi E, De Paolo R, Tentori P, et al.
ACS Chem Biol
. 2024 Sep;
19(10):2131-2140.
PMID: 39317359
Among bacteria used as anticancer vaccines, attenuated (Lm) stands out, because it spreads from one infected cancer cell to the next, induces a strong adaptive immune response, and is suitable...
5.
Strategies for single base gene editing in an immortalized human cell line by CRISPR/Cas9 technology
Corrado A, Aceto R, Miglietta S, Silvestri R, DellAnno I, Lepori I, et al.
3 Biotech
. 2024 Jan;
14(2):45.
PMID: 38261961
Supplementary Information: The online version contains supplementary material available at 10.1007/s13205-023-03878-4.
6.
Barresi E, Baldanzi C, Roncetti M, Roggia M, Baglini E, Lepori I, et al.
Eur J Med Chem
. 2023 May;
256:115446.
PMID: 37182332
BRAF represents one of the most frequently mutated protein kinase genes and BRAF mutation may be found in many types of cancer, including hairy cell leukemia (HCL), anaplastic thyroid cancer...
7.
Liu Z, Lepori I, Chordia M, Dalesandro B, Guo T, Dong J, et al.
Angew Chem Int Ed Engl
. 2023 Jan;
62(20):e202217777.
PMID: 36700874
The general lack of permeability of small molecules observed for Mycobacterium tuberculosis (Mtb) is most ascribed to its unique cell envelope. More specifically, the outer mycomembrane is hypothesized to be...
8.
Pohane A, Moore D, Lepori I, Gordon R, Nathan T, Gepford D, et al.
ACS Infect Dis
. 2023 Jan;
9(2):388.
PMID: 36652498
No abstract available.
9.
Ongwae G, Lepori I, Chordia M, Dalesandro B, Apostolos A, Siegrist M, et al.
ACS Infect Dis
. 2022 Dec;
9(1):97-110.
PMID: 36530146
Some of the most dangerous bacterial pathogens (Gram-negative and mycobacterial) deploy a formidable secondary membrane barrier to reduce the influx of exogenous molecules. For Gram-negative bacteria, this second exterior membrane...
10.
Banahene N, Gepford D, Biegas K, Swanson D, Hsu Y, Murphy B, et al.
Angew Chem Int Ed Engl
. 2022 Nov;
62(2):e202213563.
PMID: 36346622
Increasing the speed, specificity, sensitivity, and accessibility of mycobacteria detection tools are important challenges for tuberculosis (TB) research and diagnosis. In this regard, previously reported fluorogenic trehalose analogues have shown...