Ioulia Rouzina
Overview
Explore the profile of Ioulia Rouzina including associated specialties, affiliations and a list of published articles.
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Articles
74
Citations
2147
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Recent Articles
1.
Morse M, Cashen B, Rouzina I, Williams M
QRB Discov
. 2025 Feb;
6:e1.
PMID: 39944884
Single-stranded nucleic acid (ssNA) binding proteins must both stably protect ssNA transiently exposed during replication and other NA transactions, and also rapidly reorganize and dissociate to allow further NA processing....
2.
Almaqwashi A, McCauley M, Andersson J, Rouzina I, Westerlund F, Lincoln P, et al.
Biophys J
. 2025 Jan;
124(4):667-676.
PMID: 39797403
Binuclear ruthenium complexes have been investigated for potential DNA-targeted therapeutic and diagnostic applications. Studies of DNA threading intercalation, in which DNA basepairs must be broken for intercalation, have revealed means...
3.
Sundar Rajan V, Levin S, McCauley M, Williams M, Rouzina I, Wilhelmsson L, et al.
Nucleic Acids Res
. 2024 Dec;
53(1.
PMID: 39657777
It is widely appreciated that double stranded DNA (dsDNA) is subjected to strong and dynamic mechanical forces in cells. Under increasing tension B-DNA, the most stable double-stranded (ds) form of...
4.
Cashen B, Naufer M, Morse M, McCauley M, Rouzina I, Jones C, et al.
Nucleic Acids Res
. 2024 Nov;
52(22):14013-14029.
PMID: 39565204
LINE-1 (L1) is a parasitic retrotransposable DNA element, active in primates for the last 80-120 Myr. L1 has generated nearly one-third of the human genome by copying its transcripts, and...
5.
Gien H, Morse M, McCauley M, Rouzina I, Gorelick R, Williams M
Viruses
. 2024 Jun;
16(6).
PMID: 38932164
The HIV-1 nucleocapsid protein (NC) is a multifunctional viral protein necessary for HIV-1 replication. Recent studies have demonstrated that reverse transcription (RT) completes in the intact viral capsid, and the...
6.
Burdick R, Morse M, Rouzina I, Williams M, Hu W, Pathak V
Sci Adv
. 2024 Apr;
10(17):eadn7033.
PMID: 38657061
HIV-1 cores, which contain the viral genome and replication machinery, must disassemble (uncoat) during viral replication. However, the viral and host factors that trigger uncoating remain unidentified. Recent studies show...
7.
Cashen B, Morse M, Rouzina I, Karpel R, Williams M
J Mol Biol
. 2024 Mar;
436(9):168544.
PMID: 38508303
Bacteriophage T4 gene 32 protein (gp32) is a single-stranded DNA (ssDNA) binding protein essential for DNA replication. gp32 forms stable protein filaments on ssDNA through cooperative interactions between its core...
8.
Joshi J, McCauley M, Morse M, Muccio M, Kanlong J, Rocha M, et al.
Int J Mol Sci
. 2024 Feb;
25(3).
PMID: 38338688
Chloroquine has been used as a potent antimalarial, anticancer drug, and prophylactic. While chloroquine is known to interact with DNA, the details of DNA-ligand interactions have remained unclear. Here we...
9.
McCauley M, Joshi J, Becker N, Hu Q, Botuyan M, Rouzina I, et al.
Methods Mol Biol
. 2023 Oct;
2694:29-55.
PMID: 37823998
The dynamics of histone-DNA interactions govern chromosome organization and regulates the processes of transcription, replication, and repair. Accurate measurements of the energies and the kinetics of DNA binding to component...
10.
Cashen B, Morse M, Rouzina I, Karpel R, Williams M
Nucleic Acids Res
. 2023 Jul;
51(16):8587-8605.
PMID: 37449435
Bacteriophage T4 gene 32 protein (gp32) is a model single-stranded DNA (ssDNA) binding protein, essential for DNA replication. gp32 forms cooperative filaments on ssDNA through interprotein interactions between its core...