Inna Ricardo-Lax
Overview
Explore the profile of Inna Ricardo-Lax including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
519
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Recent Articles
11.
Hoffmann H, Sanchez-Rivera F, Schneider W, Luna J, Soto-Feliciano Y, Ashbrook A, et al.
Cell Host Microbe
. 2020 Dec;
29(2):267-280.e5.
PMID: 33357464
The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has devastated the global economy and claimed more than 1.7 million lives, presenting an urgent global health crisis. To identify...
12.
Schneider W, Luna J, Hoffmann H, Sanchez-Rivera F, Leal A, Ashbrook A, et al.
bioRxiv
. 2020 Oct;
PMID: 33052332
Highlights: Genome-wide CRISPR screens for SARS-CoV-2, HCoV-OC43, HCoV-NL63, and HCoV-229E coronavirus host factors.Parallel genome-wide CRISPR screening uncovered host factors and pathways with pan-coronavirus and virus-specific functional roles.Coronaviruses co-opt multiple biological...
13.
Hoffmann H, Schneider W, Sanchez-Rivera F, Luna J, Ashbrook A, Soto-Feliciano Y, et al.
bioRxiv
. 2020 Sep;
PMID: 32935098
Highlights: Focused CRISPR screens targeting host factors in the SARS-CoV-2 interactome were performed for SARS-CoV-2, HCoV-229E, HCoV-NL63, and HCoV-OC43 coronaviruses.Focused interactome CRISPR screens achieve higher resolution compared to genome-wide screens,...
14.
Michailidis E, Vercauteren K, Mancio-Silva L, Andrus L, Jahan C, Ricardo-Lax I, et al.
Proc Natl Acad Sci U S A
. 2020 Jan;
117(3):1678-1688.
PMID: 31915293
Primary human hepatocytes (PHHs) are an essential tool for modeling drug metabolism and liver disease. However, variable plating efficiencies, short lifespan in culture, and resistance to genetic manipulation have limited...
15.
Yu Y, Scheel T, Luna J, Chung H, Nishiuchi E, Scull M, et al.
PLoS Pathog
. 2018 Sep;
14(9):e1007303.
PMID: 30222761
[This corrects the article DOI: 10.1371/journal.ppat.1006694.].
16.
Yu Y, Scheel T, Luna J, Chung H, Nishiuchi E, Scull M, et al.
PLoS Pathog
. 2017 Oct;
13(10):e1006694.
PMID: 29084265
Hepatitis C virus (HCV) requires the liver specific micro-RNA (miRNA), miR-122, to replicate. This was considered unique among RNA viruses until recent discoveries of HCV-related hepaciviruses prompting the question of...
17.
Shanzer M, Adler J, Ricardo-Lax I, Reuven N, Shaul Y
Proc Natl Acad Sci U S A
. 2017 Feb;
114(7):1678-1683.
PMID: 28154141
The polyomavirus middle T antigen (PyMT) oncogene activates the cellular nonreceptor tyrosine kinase c-Src and recruits the Hippo pathway effectors, Yap (yes-associated protein) and Taz (transcriptional coactivator with PDZ-binding motif),...
18.
Ricardo-Lax I, Ramanan V, Michailidis E, Shamia T, Reuven N, Rice C, et al.
J Hepatol
. 2015 Jun;
63(4):789-96.
PMID: 26026873
Background & Aims: Hepatitis B virus (HBV) infects and replicates in quiescent hepatocytes, which are deficient in dNTPs, the critical precursors of HBV replication. Most tumor viruses promote dNTP production...