Ingrid Wernstedt Asterholm
Overview
Explore the profile of Ingrid Wernstedt Asterholm including associated specialties, affiliations and a list of published articles.
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46
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1485
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Recent Articles
1.
Hofwimmer K, de Paula Souza J, Subramanian N, Vujicic M, Rachid L, Mereau H, et al.
Nat Commun
. 2024 Sep;
15(1):7957.
PMID: 39261467
Postprandial IL-1β surges are predominant in the white adipose tissue (WAT), but its consequences are unknown. Here, we investigate the role of IL-1β in WAT energy storage and show that...
2.
Vujicic M, Broderick I, Salmantabar P, Perian C, Nilsson J, Sihlbom Wallem C, et al.
Proc Natl Acad Sci U S A
. 2024 Feb;
121(6):e2313185121.
PMID: 38300872
Efficient removal of fibrillar collagen is essential for adaptive subcutaneous adipose tissue (SAT) expansion that protects against ectopic lipid deposition during weight gain. Here, we used mice to further define...
3.
Stener-Victorin E, Eriksson G, Mohan Shrestha M, Rodriguez Paris V, Lu H, Banks J, et al.
Elife
. 2024 Jan;
12.
PMID: 38180081
Background: Polycystic ovary syndrome's (PCOS) main feature is hyperandrogenism, which is linked to a higher risk of metabolic disorders. Gene expression analyses in adipose tissue and skeletal muscle reveal dysregulated...
4.
Samad M, Ek J, Borchers S, Krieger J, Stener-Victorin E, Skibicka K, et al.
Sci Rep
. 2024 Jan;
14(1):563.
PMID: 38177175
Polycystic ovary syndrome (PCOS) is associated with symptoms of moderate to severe anxiety and depression. Hyperandrogenism is a key feature together with lower levels of the adipocyte hormone adiponectin. Androgen...
5.
Bauza-Thorbrugge M, Peris E, Zamani S, Micallef P, Paul A, Bartesaghi S, et al.
Redox Biol
. 2023 Nov;
68:102951.
PMID: 37931470
White adipose tissue browning, defined by accelerated mitochondrial metabolism and biogenesis, is considered a promising mean to treat or prevent obesity-associated metabolic disturbances. We hypothesize that redox stress acutely leads...
6.
Bauza-Thorbrugge M, Vujicic M, Chanclon B, Palsdottir V, Pillon N, Benrick A, et al.
Metabolism
. 2023 Nov;
151:155716.
PMID: 37918793
Background: The adipocyte hormone adiponectin improves insulin sensitivity and there is an inverse correlation between adiponectin levels and type-2 diabetes risk. Previous research shows that adiponectin remodels the adipose tissue...
7.
Xia Y, Andersson E, Caputo M, Cansby E, Sedda F, Font-Girones F, et al.
Mol Med
. 2023 Oct;
29(1):138.
PMID: 37864157
Objective: Non-alcoholic fatty liver disease (NAFLD), the primary hepatic consequence of obesity, is affecting about 25% of the global adult population. The aim of this study was to examine the...
8.
Paul A, Chanclon B, Brannmark C, Wittung-Stafshede P, Olofsson C, Asterholm I, et al.
J Cell Biochem
. 2023 Jan;
124(3):382-395.
PMID: 36715685
Brown adipose tissue (BAT) consists of highly metabolically active adipocytes that catabolize nutrients to produce heat. Playing an active role in triacylglycerol (TAG) clearance, research has shown that dietary fatty...
9.
Crewe C, Chen S, Bu D, Gliniak C, Asterholm I, Yu X, et al.
Diabetes
. 2022 Jul;
71(12):2496-2512.
PMID: 35880782
Caveolin-1 (cav1) is an important structural and signaling component of plasma membrane invaginations called caveolae and is abundant in adipocytes. As previously reported, adipocyte-specific ablation of the cav1 gene (ad-cav1...
10.
Bauza-Thorbrugge M, Banke E, Chanclon B, Peris E, Wu Y, Musovic S, et al.
Mol Metab
. 2022 Jun;
63:101535.
PMID: 35760318
Objective: Sarco/endoplasmic reticulum Ca-ATPase (SERCA) transports Ca from the cytosol into the endoplasmic retitculum (ER) and is essential for appropriate regulation of intracellular Ca homeostasis. The objective of this study...