Ingrid Wernstedt Asterholm
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Explore the profile of Ingrid Wernstedt Asterholm including associated specialties, affiliations and a list of published articles.
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46
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1485
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Recent Articles
11.
Micallef P, Vujicic M, Wu Y, Peris E, Wang Y, Chanclon B, et al.
Front Immunol
. 2022 Jun;
13:914956.
PMID: 35720277
The adipose tissue undergoes substantial tissue remodeling during weight gain-induced expansion as well as in response to the mechanical and immunological stresses from a growing tumor. We identified the C1q/TNF-related...
12.
Mohan Shrestha M, Wermelin S, Stener-Victorin E, Asterholm I, Benrick A
Int J Mol Sci
. 2022 May;
23(9).
PMID: 35563332
Adiponectin administration to pregnant mice decreases nutrient transport and fetal growth. An adiponectin deficiency, on the other hand, as seen in obese women during pregnancy, alters fetal growth; however, the...
13.
Musovic S, Komai A, Said M, Mohan Shrestha M, Wu Y, Asterholm I, et al.
Mol Cell Endocrinol
. 2022 Mar;
549:111619.
PMID: 35337901
White adipocyte adiponectin exocytosis is triggered by cAMP and a concomitant increase of cytosolic Ca potentiates its release. White adipose tissue is richly innervated by sympathetic nerves co-releasing noradrenaline (NA)...
14.
Maric I, Krieger J, van der Velden P, Borchers S, Asker M, Vujicic M, et al.
Front Nutr
. 2022 Mar;
9:828522.
PMID: 35284452
Prevalence and health consequences of obesity differ between men and women. Yet, most preclinical studies investigating the etiology of obesity have, to date, been conducted in male rodents. Notably, diet...
15.
Kim A, Knudsen J, Madara J, Benrick A, Hill T, Abdul Kadir L, et al.
Elife
. 2021 Nov;
10.
PMID: 34787082
Insulin-induced hypoglycemia is a major treatment barrier in type-1 diabetes (T1D). Accordingly, it is important that we understand the mechanisms regulating the circulating levels of glucagon. Varying glucose over the...
16.
Micallef P, Wu Y, Bauza-Thorbrugge M, Chanclon B, Vujicic M, Peris E, et al.
Int J Mol Sci
. 2021 Nov;
22(21).
PMID: 34769312
We sought to identify therapeutic targets for breast cancer by investigating the metabolic symbiosis between breast cancer and adipose tissue. To this end, we compared orthotopic E0771 breast cancer tumors...
17.
Lagerquist M, Gustafsson K, Henning P, Farman H, Wu J, Sjogren K, et al.
Sci Rep
. 2021 Jul;
11(1):14177.
PMID: 34238965
Obesity has previously been thought to protect bone since high body weight and body mass index are associated with high bone mass. However, some more recent studies suggest that increased...
18.
Wu Y, Chanclon B, Micallef P, Stener-Victorin E, Asterholm I, Benrick A
FASEB J
. 2021 Mar;
35(4):e21299.
PMID: 33715227
Hyperandrogenism is the main characteristic of polycystic ovary syndrome, which affects placental function and fetal growth, and leads to reproductive and metabolic dysfunction in female offspring. Adiponectin acts on the...
19.
Chanclon B, Wu Y, Vujicic M, Bauza-Thorbrugge M, Banke E, Micallef P, et al.
Int J Obes (Lond)
. 2020 Aug;
44(11):2323-2334.
PMID: 32843711
Background/objectives: Visceral adiposity is associated with increased diabetes risk, while expansion of subcutaneous adipose tissue may be protective. However, the visceral compartment contains different fat depots. Peripancreatic adipose tissue (PAT)...
20.
Brannmark C, Kay E, Ortegren Kugelberg U, Chanclon B, Mohan Shrestha M, Asterholm I, et al.
J Endocrinol
. 2020 Jul;
247(1):25-38.
PMID: 32668406
Here we have investigated the role of the protein caveolin 1 (Cav1) and caveolae in the secretion of the white adipocyte hormone adiponectin. Using mouse primary subcutaneous adipocytes genetically depleted...