Ines A Drinnenberg
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Explore the profile of Ines A Drinnenberg including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
840
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Recent Articles
1.
Marques A, Drinnenberg I
Curr Opin Cell Biol
. 2025 Feb;
93:102484.
PMID: 39983583
Centromeres are essential chromosomal regions responsible for ensuring proper chromosome segregation during cell division. Unlike monocentric chromosomes, which have a single centromeric region, holocentric chromosomes distribute centromeric activity along their...
2.
Kassamaly I, Cornilleau G, Drinnenberg I, Tran P
MicroPubl Biol
. 2022 Sep;
2022.
PMID: 36082020
We previously showed that the silkworm holocentric spindles are square-shaped, compared to the canonical oval shape of human monocentric spindles (Vanpoperinghe et al. 2021). Further, while kinesin-5 depletion resulted in...
3.
Senaratne A, Cortes-Silva N, Drinnenberg I
Semin Cell Dev Biol
. 2022 Jan;
127:90-99.
PMID: 35031207
Centromeres are specialized chromosomal regions that recruit kinetochore proteins and mediate spindle microtubule attachment to ensure faithful chromosome segregation during mitosis and meiosis. Centromeres can be restricted to one region...
4.
Vanpoperinghe L, Carlier-Grynkorn F, Cornilleau G, Kusakabe T, Drinnenberg I, Tran P
MicroPubl Biol
. 2021 Sep;
2021.
PMID: 34514356
Proper chromosome segregation during mitosis requires both the assembly of a microtubule (MT)-based spindle and the assembly of DNA-centromere-based kinetochore structure. Kinetochore-to-MT attachment enables chromosome separation. Monocentric cells, such as...
5.
Rosin L, Gil Jr J, Drinnenberg I, Lei E
PLoS Genet
. 2021 Jul;
17(7):e1009700.
PMID: 34319984
Accurate chromosome segregation during meiosis is essential for reproductive success. Yet, many fundamental aspects of meiosis remain unclear, including the mechanisms regulating homolog pairing across species. This gap is partially...
6.
Senaratne A, Muller H, Fryer K, Kawamoto M, Katsuma S, Drinnenberg I
Curr Biol
. 2020 Oct;
31(1):173-181.e7.
PMID: 33125865
Despite the essentiality for faithful chromosome segregation, centromere architectures are diverse among eukaryotes and embody two main configurations: mono- and holocentromeres, referring, respectively, to localized or unrestricted distribution of centromeric...
7.
Getz M, Weinberg D, Drinnenberg I, Fink G, Bartel D
Nucleic Acids Res
. 2020 Jun;
48(13):7404-7420.
PMID: 32501509
RNA interference (RNAi) is a gene-silencing pathway that can play roles in viral defense, transposon silencing, heterochromatin formation and post-transcriptional gene silencing. Although absent from Saccharomyces cerevisiae, RNAi is present...
8.
Cortes-Silva N, Ulmer J, Kiuchi T, Hsieh E, Cornilleau G, Ladid I, et al.
Curr Biol
. 2020 Feb;
30(4):561-572.e10.
PMID: 32032508
Accurate chromosome segregation requires assembly of the multiprotein kinetochore complex at centromeres. In most eukaryotes, kinetochore assembly is primed by the histone H3 variant CenH3 (also called CENP-A), which physically...
9.
Drinnenberg I, Berger F, Elsasser S, Andersen P, Ausio J, Bickmore W, et al.
Development
. 2019 Sep;
146(19).
PMID: 31558570
Over the past few years, interest in chromatin and its evolution has grown. To further advance these interests, we organized a workshop with the support of The Company of Biologists...
10.
Molaro A, Drinnenberg I
Methods Mol Biol
. 2018 Aug;
1832:273-291.
PMID: 30073533
Histones wrap DNA to form nucleosomes that package eukaryotic genomes. Histone variants have evolved for diverse functions including gene expression, DNA repair, epigenetic silencing, and chromosome segregation. With the rapid...