Ine Vanderleyden
Overview
Explore the profile of Ine Vanderleyden including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
182
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0
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Recent Articles
1.
Silva-Cayetano A, Fra-Bido S, Robert P, Innocentin S, Burton A, Watson E, et al.
Nat Immunol
. 2023 May;
24(7):1124-1137.
PMID: 37217705
The magnitude and quality of the germinal center (GC) response decline with age, resulting in poor vaccine-induced immunity in older individuals. A functional GC requires the co-ordination of multiple cell...
2.
Stebegg M, Bignon A, Hill D, Silva-Cayetano A, Krueger C, Vanderleyden I, et al.
Elife
. 2020 Mar;
9.
PMID: 32204792
Germinal centres (GCs) are T follicular helper cell (Tfh)-dependent structures that form in response to vaccination, producing long-lived antibody secreting plasma cells and memory B cells that protect against subsequent...
3.
Vanderleyden I, Fra-Bido S, Innocentin S, Stebegg M, Okkenhaug H, Evans-Bailey N, et al.
Cell Rep
. 2020 Jan;
30(3):611-619.e4.
PMID: 31968240
The germinal center (GC) response is critical for generating high-affinity humoral immunity and immunological memory, which forms the basis of successful immunization. Control of the GC response is thought to...
4.
Vanderleyden I, Linterman M
Methods Mol Biol
. 2017 Jun;
1623:87-93.
PMID: 28589349
Follicular regulatory T cells are a subset of Foxp3 regulatory T cells that migrate into the B cell follicle after infection or immunization and modulate the germinal center response. The...
5.
Afzali B, Gronholm J, Vandrovcova J, OBrien C, Sun H, Vanderleyden I, et al.
Nat Immunol
. 2017 May;
18(7):813-823.
PMID: 28530713
The transcriptional programs that guide lymphocyte differentiation depend on the precise expression and timing of transcription factors (TFs). The TF BACH2 is essential for T and B lymphocytes and is...
6.
Vanderleyden I, Linterman M, Smith K
Arthritis Res Ther
. 2015 Jan;
16(5):471.
PMID: 25606598
Germinal centres (GCs) are specialised lymphoid microenvironments that form in secondary B-cell follicles upon exposure to T-dependent antigens. In the GC, clonal expansion, selection and differentiation of GC B cells...