Indrajit Sahu
Overview
Explore the profile of Indrajit Sahu including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
18
Citations
375
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
P T B, Sahu I
Biochem Soc Trans
. 2024 Apr;
52(2):627-637.
PMID: 38572966
Functional consequences of protein ubiquitination have gone far beyond the degradation regulation as was initially imagined during its discovery 40 years back. The state-of-the-art has revealed the plethora of signaling...
2.
Sahoo M, Lavy T, Cohen N, Sahu I, Kleifeld O
Mol Cell Proteomics
. 2024 Jan;
23(3):100728.
PMID: 38296025
Proteasomes are multisubunit, multicatalytic protein complexes present in eukaryotic cells that degrade misfolded, damaged, or unstructured proteins. In this study, we used an activity-guided proteomic methodology based on a fluorogenic...
3.
Sahu I, Zhu H, Buhrlage S, Marto J
Biochim Biophys Acta Gene Regul Mech
. 2023 Apr;
1866(2):194940.
PMID: 37121501
As originally described some 40 years ago, protein ubiquitination was thought to serve primarily as a static mark for protein degradation. In the ensuing years, it has become clear that...
4.
Sahu I, Bajorek M, Tan X, Srividya M, Krutauz D, Reis N, et al.
Biomolecules
. 2023 Mar;
13(3).
PMID: 36979414
The proteolytic active sites of the 26S proteasome are sequestered within the catalytic chamber of its 20S core particle (CP). Access to this chamber is through a narrow channel defined...
5.
Sahu I, Sahoo M, Kleifeld O, Glickman M
Methods Mol Biol
. 2022 Nov;
2602:229-241.
PMID: 36446979
Analyzing intracellular peptides generated by proteasomes is highly informative to understand the spatiotemporal regulation of protein homeostasis. A large portion of eukaryotic proteins is proteolyzed within the 20S core particle...
6.
Sahu I, Mali S, Sulkshane P, Xu C, Rozenberg A, Morag R, et al.
Nat Commun
. 2021 Oct;
12(1):6173.
PMID: 34702852
The proteasome, the primary protease for ubiquitin-dependent proteolysis in eukaryotes, is usually found as a mixture of 30S, 26S, and 20S complexes. These complexes have common catalytic sites, which makes...
7.
Tiwari R, Ganguli N, Alam H, Sahu I, Vadivel C, Sinha S, et al.
Cell Biol Int
. 2021 Apr;
45(8):1720-1732.
PMID: 33847415
Keratin 8/18, the predominant keratin pair of simple epithelia, is known to be aberrantly expressed in several squamous cell carcinomas (SCCs), where its expression is often correlated with increased invasion,...
8.
Sahu I, Glickman M
Biochem Soc Trans
. 2021 Mar;
49(2):629-644.
PMID: 33729481
Ubiquitination is the major criteria for the recognition of a substrate-protein by the 26S proteasome. Additionally, a disordered segment on the substrate - either intrinsic or induced - is critical...
9.
Sahu I, Glickman M
Biomolecules
. 2021 Jan;
11(2).
PMID: 33498876
Four decades of proteasome research have yielded extensive information on ubiquitin-dependent proteolysis. The archetype of proteasomes is a 20S barrel-shaped complex that does not rely on ubiquitin as a degradation...
10.
Sahu I, Nanaware P, Mane M, Mulla S, Roy S, Venkatraman P
Int J Stem Cells
. 2019 Sep;
12(3):463-473.
PMID: 31474027
PSMD10, a proteasome assembly chaperone, is a widely known oncoprotein which aspects many hall mark properties of cancer. However, except proteasome assembly chaperon function its role in normal cell function...