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Prasanna Venkatraman

Explore the profile of Prasanna Venkatraman including associated specialties, affiliations and a list of published articles. Areas
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Articles 33
Citations 366
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Recent Articles
1.
Sundararajan R, Hegde S, Panda A, Christie J, Gadewal N, Venkatraman P
Commun Biol . 2025 Jan; 8(1):55. PMID: 39814910
Why cancer cells disproportionately accumulate polyubiquitinated proteotoxic proteins despite high proteasomal activity is an outstanding question. While mis-regulated ubiquitination is a contributing factor, here we show that a structurally-perturbed and...
2.
Christie J, Anthony C, Harish M, Mudartha D, Ud Din Farooqee S, Venkatraman P
FEBS J . 2023 Sep; 290(23):5581-5604. PMID: 37665644
Functional networks in cells are created by physical, genetic, and regulatory interactions. Mapping them and annotating their functions by available methods remains a challenge. We use affinity purification mass spectrometry...
3.
Burikhanov R, Ganguly S, Ellingson S, Sviripa V, Araujo N, Li S, et al.
Am J Cancer Res . 2023 Apr; 13(3):976-991. PMID: 37034206
Lung cancer is the leading cause of cancer-related deaths. Lung cancer cells develop resistance to apoptosis by suppressing the secretion of the tumor suppressor Par-4 protein (also known as PAWR)...
4.
Medur Gurushankar M, Dalvi S, Venkatraman P
Protein Sci . 2022 Nov; 31(12):e4515. PMID: 36382986
Protein folding and unfolding is a complex process, underscored by the many proteotoxic diseases associated with misfolded proteins. Mapping pathways from a native structure to an unfolded protein or vice...
5.
Mulla S, Venkatraman P
Int J Biochem Cell Biol . 2022 Apr; 146:106209. PMID: 35378311
NFκB is a critical rapid-acting transcription factor that protects cancer cells from programmed cell death induced by stress or therapy. While NFκB works in nexus with non-classical oncoproteins such as...
6.
T S S, Dalvi S, Venkatraman P, Vemparala S
Proteins . 2022 Jan; 90(5):1179-1189. PMID: 35006623
Mutation of an invariant aspartate residue in the binding pocket of 14-3-3ζ isoform to alanine dramatically reduced phosphopeptide binding and induced opening of the binding pocket. Here we use extensive...
7.
M G M, Chikhale R, Nanaware P, Dalvi S, Venkatraman P
Eur J Pharmacol . 2021 Dec; 915:174718. PMID: 34953804
Background: PSMD10, a proteasomal chaperone is also an oncoprotein. Overexpression of PSMD10 is associated with poor prognosis and survival in many cancers. Therefore, PSMD10 is a sought-after drug target in...
8.
Ud Din Farooqee S, Christie J, Venkatraman P
Biochem Biophys Res Commun . 2021 Jun; 563:105-112. PMID: 34077860
Capitalizing on an unexpected observation that multiple free ribosomal proteins co-purify/pull-down with PSMD9, we report here for the first time that PSMD9 is necessary to maintain the morphology and integrity...
9.
Rao M, Venkatraman P, Mukhopadhyay D, Roychoudhury S, Vanderford N, Rangnekar V
Genes Cancer . 2021 May; 12:65-68. PMID: 34046148
No abstract available.
10.
Bose A, Modi K, Dey S, Dalvi S, Nadkarni P, Sudarshan M, et al.
Genes Cells . 2021 Apr; 26(6):426-446. PMID: 33813791
14-3-3 proteins bind to ligands via phospho-serine containing consensus motifs. However, the molecular mechanisms underlying complex formation and dissociation between 14-3-3 proteins and their ligands remain unclear. We identified two...