Ilya Shmulevich
Overview
Explore the profile of Ilya Shmulevich including associated specialties, affiliations and a list of published articles.
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147
Citations
18891
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Recent Articles
1.
Ellrott K, Wong C, Yau C, Castro M, Lee J, Karlberg B, et al.
Cancer Cell
. 2025 Jan;
43(2):195-212.e11.
PMID: 39753139
Molecular subtypes, such as defined by The Cancer Genome Atlas (TCGA), delineate a cancer's underlying biology, bringing hope to inform a patient's prognosis and treatment plan. However, most approaches used...
2.
Nikolic V, Echlin M, Aguilar B, Shmulevich I
PLoS One
. 2024 Dec;
19(12):e0315300.
PMID: 39636827
[This corrects the article DOI: 10.1371/journal.pone.0282122.].
3.
L Rocha H, Aguilar B, Getz M, Shmulevich I, Macklin P
NPJ Syst Biol Appl
. 2024 Dec;
10(1):144.
PMID: 39627216
Metastasis is the leading cause of death in patients with cancer, driving considerable scientific and clinical interest in immunosurveillance of micrometastases. We investigated this process by creating a multiscale mathematical...
4.
Qin G, Narsinh K, Wei Q, Roach J, Joshi A, Goetz S, et al.
bioRxiv
. 2024 Nov;
PMID: 39605475
As large clinical and multiomics datasets and knowledge resources accumulate, they need to be transformed into computable and actionable information to support automated reasoning. These datasets range from laboratory experiment...
5.
Qin G, Zhang Y, Tyner J, Kemp C, Shmulevich I
iScience
. 2024 Sep;
27(9):110755.
PMID: 39280607
Acute myeloid leukemia (AML) is a highly aggressive and heterogeneous disease, underscoring the need for improved therapeutic options and methods to optimally predict responses. With the wealth of available data...
6.
Qin G, Dai J, Chien S, Martins T, Loera B, Nguyen Q, et al.
Clin Cancer Res
. 2024 Apr;
30(12):2659-2671.
PMID: 38619278
Purpose: The inherent genetic heterogeneity of acute myeloid leukemia (AML) has challenged the development of precise and effective therapies. The objective of this study was to elucidate the genomic basis...
7.
Laubenbacher R, Adler F, An G, Castiglione F, Eubank S, Fonseca L, et al.
Front Digit Health
. 2024 Mar;
6:1349595.
PMID: 38515550
A fundamental challenge for personalized medicine is to capture enough of the complexity of an individual patient to determine an optimal way to keep them healthy or restore their health....
8.
Laubenbacher R, Adler F, An G, Castiglione F, Eubank S, Fonseca L, et al.
NPJ Syst Biol Appl
. 2024 Feb;
10(1):19.
PMID: 38365857
Medical digital twins are computational models of human biology relevant to a given medical condition, which are tailored to an individual patient, thereby predicting the course of disease and individualized...
9.
Zhang Y, Qin G, Aguilar B, Rappaport N, Yurkovich J, Pflieger L, et al.
Front Digit Health
. 2024 Feb;
6:1336050.
PMID: 38343907
Introduction: A digital twin is a virtual representation of a patient's disease, facilitating real-time monitoring, analysis, and simulation. This enables the prediction of disease progression, optimization of care delivery, and...
10.
Nikolic V, Echlin M, Aguilar B, Shmulevich I
PLoS One
. 2023 Apr;
18(4):e0282122.
PMID: 37023084
The capacity of cells to process information is currently used to design cell-based tools for ecological, industrial, and biomedical applications such as detecting dangerous chemicals or for bioremediation. In most...