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Ilhan Tomris

Explore the profile of Ilhan Tomris including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 258
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Recent Articles
1.
Tomris I, Kimpel A, Liang R, van der Woude R, Boons G, Li Z, et al.
ACS Infect Dis . 2024 Oct; 10(11):3880-3890. PMID: 39394950
Coronaviruses (CoVs) recognize a wide array of protein and glycan receptors by using the S1 subunit of the spike (S) glycoprotein. The S1 subunit contains two functional domains: the N-terminal...
2.
Tomris I, Kimpel A, Liang R, van der Woude R, Boons G, Li Z, et al.
bioRxiv . 2024 Jun; PMID: 38826377
Coronaviruses recognize a wide array of protein and glycan receptors using the S1 subunit of the spike (S) glycoprotein. The S1 subunit contains two functional domains: the N-terminal (S1-NTD) and...
3.
Tomris I, van der Woude R, de Paiva Froes Rocha R, Torrents de la Pena A, Ward A, de Vries R
Protein Sci . 2024 Mar; 33(4):e4974. PMID: 38533540
Enveloped viruses carry one or multiple proteins with receptor-binding functionalities. Functional receptors can be glycans, proteinaceous, or both; therefore, recombinant protein approaches are instrumental in attaining new insights regarding viral...
4.
Tomris I, Unione L, Nguyen L, Zaree P, Bouwman K, Liu L, et al.
ACS Chem Biol . 2023 Apr; 18(5):1180-1191. PMID: 37104622
SARS-CoV-2 viruses engage ACE2 as a functional receptor with their spike protein. The S1 domain of the spike protein contains a C-terminal receptor binding domain (RBD) and an N-terminal domain...
5.
Sun L, Chopra P, Tomris I, van der Woude R, Liu L, de Vries R, et al.
JACS Au . 2023 Apr; 3(4):1185-1195. PMID: 37101566
The emergence of new SARS-CoV-2 variants and the dangers of long-covid necessitate the development of broad-acting therapeutics that can reduce viral burden. SARS-CoV-2 employs heparan sulfate (HS) as an initial...
6.
Zaree P, Tomris I, de Vos S, van der Woude R, Flesch F, Klein Gebbink R, et al.
RSC Adv . 2023 Mar; 13(14):9756-9760. PMID: 36994086
A novel miniaturized sensor for electrochemical detection that contains graphene- and gold nanoparticles was functionalized with proteins. Using cyclic voltammetry (CV) and differential pulse voltammetry (DPV) it was possible to...
7.
Tomris I, Unione L, Nguyen L, Zaree P, Bouwman K, Liu L, et al.
bioRxiv . 2022 Oct; PMID: 36263070
Graphical Abstract: Synopsis: Coronaviruses utilize their N-terminal domain (NTD) for initial reversible low-affinity interaction to (sialylated) glycans. This initial low-affinity/high-avidity engagement enables viral surfing on the target membrane, potentially followed...
8.
Tomris I, Bouwman K, Adolfs Y, Noack D, van der Woude R, Kerster G, et al.
PLoS Pathog . 2022 Mar; 18(3):e1010340. PMID: 35255100
SARS-CoV-2 attaches to angiotensin-converting enzyme 2 (ACE2) to gain entry into cells after which the spike protein is cleaved by the transmembrane serine protease 2 (TMPRSS2) to facilitate viral-host membrane...
9.
Spruit C, Zhu X, Tomris I, Rios-Carrasco M, Han A, Broszeit F, et al.
J Virol . 2022 Jan; 96(5):e0212021. PMID: 35044215
Influenza A viruses (IAV) initiate infection by binding to glycans with terminal sialic acids on the cell surface. Hosts of IAV variably express two major forms of sialic acid, -acetylneuraminic...
10.
Nemanichvili N, Berends A, Tomris I, Barnard K, Parrish C, Grone A, et al.
Vet Microbiol . 2021 Dec; 264:109298. PMID: 34906835
The influenza D virus (IDV) uses a trimeric hemagglutinin-esterase fusion protein (HEF) for attachment to 9-O-acetylated sialic acid receptors on the cell surface of host species. So far research has...