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Igor V Makunin

Explore the profile of Igor V Makunin including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 1688
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Recent Articles
1.
Makunin I, Kolesnikova T, Andreyenkova N
Genome Biol Evol . 2014 Jul; 6(8):2050-60. PMID: 25062918
Many late replicating regions are underreplicated in polytene chromosomes of Drosophila melanogaster. These regions contain silenced chromatin and overlap long syntenic blocks of conserved gene order in drosophilids. In this...
2.
Park D, Tao K, Le Calvez-Kelm F, Nguyen-Dumont T, Robinot N, Hammet F, et al.
Cancer Discov . 2014 Jul; 4(7):804-15. PMID: 25050558
Unlabelled: Approximately half of the familial aggregation of breast cancer remains unexplained. A multiple-case breast cancer family exome-sequencing study identified three likely pathogenic mutations in RINT1 (NM_021930.4) not present in...
3.
Andreyenkova N, Kolesnikova T, Makunin I, Pokholkova G, Boldyreva L, Zykova T, et al.
PLoS One . 2014 Jan; 8(12):e83319. PMID: 24391753
Drosophila chromosomes are organized into distinct domains differing in their predominant chromatin composition, replication timing and evolutionary conservation. We show on a genome-wide level that genes whose order has remained...
4.
Makunin I, Shloma V, Stephen S, Pheasant M, Belyakin S
PLoS One . 2013 Dec; 8(12):e82362. PMID: 24349264
Metazoan genomes contain many ultra-conserved elements (UCEs), long sequences identical between distant species. In this study we identified UCEs in drosophilid and vertebrate species with a similar level of phylogenetic...
5.
Jung C, Makunin I, Mattick J
Genomics . 2010 Jul; 96(3):154-66. PMID: 20595017
Non-protein-coding DNA comprises the majority of animal genomes but its functions are largely unknown. We identified over 17,000 different tetranucleotide pairs in the Drosophila melanogaster genome that are over-represented at...
6.
Babenko V, Makunin I, Brusentsova I, Belyaeva E, Maksimov D, Belyakin S, et al.
BMC Genomics . 2010 May; 11:318. PMID: 20492674
Background: Eukaryotic genomes are organized in extended domains with distinct features intimately linking genome structure, replication pattern and chromatin state. Recently we identified a set of long late replicating euchromatic...
7.
Jung C, Hansen M, Makunin I, Korbie D, Mattick J
BMC Genomics . 2010 Feb; 11:77. PMID: 20113528
Background: The increasing interest in small non-coding RNAs (ncRNAs) such as microRNAs (miRNAs), small interfering RNAs (siRNAs) and Piwi-interacting RNAs (piRNAs) and recent advances in sequencing technology have yielded large...
8.
Yurlova A, Makunin I, Kolesnikova T, Posukh O, Belyaeva E, Zhimulev I
Genetics . 2009 Jul; 183(1):119-29. PMID: 19596903
Different genomic regions replicate at a distinct time during S-phase. The SuUR mutation alters replication timing and the polytenization level of intercalary and pericentric heterochromatin in Drosophila melanogaster salivary gland...
9.
Solda G, Makunin I, Sezerman O, Corradin A, Corti G, Guffanti A
Brief Bioinform . 2009 Apr; 10(5):475-89. PMID: 19383843
Non-protein coding RNAs (ncRNAs) have emerged as a vast and heterogeneous portion of eukaryotic transcriptomes. Several ncRNA families, either short (<200 nucleotides, nt) or long (>200 nt), have been described...
10.
Simons C, Makunin I, Pheasant M, Mattick J
BMC Genomics . 2007 Dec; 8:470. PMID: 18093339
Background: We recently reported the existence of large numbers of regions up to 80 kb long that lack transposon insertions in the human, mouse and opossum genomes. These regions are...