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Werner Muller-Esterl

Explore the profile of Werner Muller-Esterl including associated specialties, affiliations and a list of published articles. Areas
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Articles 64
Citations 2281
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Kenne E, Rasmuson J, Renne T, Vieira M, Muller-Esterl W, Herwald H, et al.
FASEB J . 2018 Oct; 33(2):2599-2609. PMID: 30281335
Neutrophil recruitment and plasma exudation are key elements in the immune response to injury or infection. Activated neutrophils stimulate opening of the endothelial barrier; however, the underlying mechanisms have remained...
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Hoffmeister M, Prelle C, Kuchler P, Kovacevic I, Moser M, Muller-Esterl W, et al.
PLoS One . 2014 Dec; 9(12):e116150. PMID: 25546391
Holoprosencephaly is a common developmental disorder in humans characterised by incomplete brain hemisphere separation and midface anomalies. The etiology of holoprosencephaly is heterogeneous with environmental and genetic causes, but for...
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Kovacevic I, Hu J, Siehoff-Icking A, Opitz N, Griffin A, Perkins A, et al.
EMBO J . 2012 Jul; 31(15):3309-22. PMID: 22751148
F-BAR proteins are multivalent adaptors that link plasma membrane and cytoskeleton and coordinate cellular processes such as membrane protrusion and migration. Yet, little is known about the function of F-BAR...
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Cote J, Bovenzi V, Savard M, Dubuc C, Fortier A, Neugebauer W, et al.
PLoS One . 2012 May; 7(5):e37485. PMID: 22629405
Treatment of malignant glioma with chemotherapy is limited mostly because of delivery impediment related to the blood-brain tumor barrier (BTB). B1 receptors (B1R), inducible prototypical G-protein coupled receptors (GPCR) can...
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Oschatz C, Maas C, Lecher B, Jansen T, Bjorkqvist J, Tradler T, et al.
Immunity . 2011 Feb; 34(2):258-68. PMID: 21349432
Activated mast cells trigger edema in allergic and inflammatory disease. We report a paracrine mechanism by which mast cell-released heparin increases vascular permeability in vivo. Heparin activated the protease factor...
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Akesson P, Herwald H, Rasmussen M, Hakansson K, Abrahamson M, Hasan A, et al.
Microbiology (Reading) . 2010 Aug; 156(Pt 12):3660-3668. PMID: 20705662
Since the late 1980s, a worldwide increase of severe Streptococcus pyogenes infections has been associated with strains of the M1 serotype, strains which all secrete the streptococcal inhibitor of complement-mediated...
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Trabold R, Eros C, Zweckberger K, Relton J, Beck H, Nussberger J, et al.
J Cereb Blood Flow Metab . 2009 Sep; 30(1):130-9. PMID: 19773800
Inflammatory mechanisms are known to contribute to the pathophysiology of traumatic brain injury (TBI). Since bradykinin is one of the first mediators activated during inflammation, we investigated the role of...
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Schmidt M, Bicker F, Nikolic I, Meister J, Babuke T, Picuric S, et al.
Nat Cell Biol . 2009 Jun; 11(7):873-80. PMID: 19503073
Epidermal growth factor-like domain 7 (EGFL7) is a secreted factor implicated in cellular responses such as cell migration and blood vessel formation; however the molecular mechanisms underlying the effects of...
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Kahn R, Hellmark T, Leeb-Lundberg L, Akbari N, Todiras M, Olofsson T, et al.
J Immunol . 2009 Jun; 182(12):7906-15. PMID: 19494315
The kinin-forming pathway is activated on endothelial cells and neutrophils when high-molecular weight kininogen (HK) is cleaved by plasma kallikrein liberating bradykinin, a potent mediator of inflammation. Kinins are released...