Ian Davis
Overview
Explore the profile of Ian Davis including associated specialties, affiliations and a list of published articles.
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Articles
96
Citations
1080
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Recent Articles
1.
Yang Y, Davis I, Altman R, Liu A
J Biol Chem
. 2024 Oct;
300(11):107878.
PMID: 39395800
ACMSD (α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase) is a key metalloenzyme critical for regulating de novo endogenous NAD/NADH biosynthesis through the tryptophan-kynurenine pathway. This decarboxylase is a recognized target implicated in mitochondrial diseases and...
2.
Allegretti J, Kelly C, Louie T, Fischer M, Hota S, Misra B, et al.
Gastroenterology
. 2024 Oct;
168(2):357-366.e3.
PMID: 39366468
Background & Aims: Recurrent Clostridioides difficile infections (CDIs) remain common. While novel microbiome therapeutics gain approval, the efficacy of a full-spectrum, oral microbiome therapeutic is unknown. This study aimed to...
3.
Li J, Duan R, Traore E, Nguyen R, Davis I, Griffth W, et al.
Angew Chem Int Ed Engl
. 2024 Sep;
63(49):e202407018.
PMID: 39300819
Bifunctional catalase-peroxidase (KatG) features a posttranslational methionine-tyrosine-tryptophan (MYW) crosslinked cofactor crucial for its catalase function, enabling pathogens to neutralize hydrogen peroxide during infection. We discovered the presence of indole nitrogen-linked...
4.
Cohen C, Balinandi S, Kuehne A, Rock M, Bonagofski L, Ricks K, et al.
J Infect Dis
. 2024 Sep;
PMID: 39248523
Evaluating the adaptive immune responses to natural infection with Crimean-Congo hemorrhagic fever (CCHF) virus (CCHFV) in human survivors is critical to the development of medical countermeasures. However, the correlates of...
5.
Espeland M, Harada A, Ross J, Bancks M, Pajewski N, Simpson F, et al.
J Am Geriatr Soc
. 2024 Jul;
72(9):2759-2769.
PMID: 38946518
Background: Type 2 diabetes mellitus and overweight/obesity increase healthcare costs. Both are also associated with accelerated aging. However, the contributions of this accelerated aging to increased healthcare costs are unknown....
6.
Conte B, Shen C, Thompson P, Davis I, Casey D
Am J Clin Oncol
. 2023 Dec;
47(3):128-131.
PMID: 38088232
Background: As radiation therapy (RT) for Wilms tumor (WT) evolves with more conformal techniques, it is necessary to evaluate patterns of failure and toxicity. We sought to determine the rate...
7.
Lerminiaux N, Mitchell R, Bartoszko J, Davis I, Ellis C, Fakharuddin K, et al.
Antimicrob Agents Chemother
. 2023 Nov;
67(12):e0086023.
PMID: 37971242
Carbapenems are considered last-resort antibiotics for the treatment of infections caused by multidrug-resistant , but carbapenem resistance due to acquisition of carbapenemase genes is a growing threat that has been...
8.
Simms E, McCracken G, Hatchette T, McNeil S, Davis I, Whelan N, et al.
Microbiol Spectr
. 2023 Nov;
11(6):e0277223.
PMID: 37962351
In hospitals during the COVID-19 pandemic, laboratory testing was important to reduce SARS-CoV-2 transmissions, while facilitating patient flow in the emergency department and pre-operative settings, and allowing for the safe...
9.
Nguyen R, Davis I, Dasgupta M, Wang Y, Simon P, Butryn A, et al.
J Am Chem Soc
. 2023 Nov;
145(46):25120-25133.
PMID: 37939223
The P450 enzyme CYP121 from catalyzes a carbon-carbon (C-C) bond coupling cyclization of the dityrosine substrate containing a diketopiperazine ring, (l-tyrosine-l-tyrosine) (cYY). An unusual high-spin ( = 5/2) ferric intermediate...
10.
Davis I, Payne J, Olguin V, Sanders M, Clements T, Stefan C, et al.
Front Microbiol
. 2023 Sep;
14:1243523.
PMID: 37744911
Human monkeypox (mpox) has recently become a global public health emergency; however, assays that detect mpox infection are not widely available, largely due to cross-reactivity within the genus. Immunoassay development...