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Jiasong Li

Explore the profile of Jiasong Li including associated specialties, affiliations and a list of published articles. Areas
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Articles 65
Citations 1356
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Recent Articles
1.
Shishikura K, Li J, Chen Y, McKnight N, Bustin K, Barr E, et al.
bioRxiv . 2025 Jan; PMID: 39803451
The vasodilator hydralazine (HYZ) has been used clinically for ~ 70 years and remains on the World Health Organization's List of Essential Medicines as a therapy for preeclampsia. Despite its...
2.
Zhang T, Lv H, Li J, Zhang S, Zhang J, Wang S, et al.
Front Immunol . 2025 Jan; 15():1503316. PMID: 39776906
Background: The occurrence of immune-related adverse events (irAEs) seemed to be associated with better outcomes in advanced gastric cancer (AGC) patients. However, research focusing on the impact of the single-organ...
3.
Ji Z, Li J, Zhang S, Jia Y, Zhang J, Guo Z
Front Immunol . 2024 Dec; 15():1480520. PMID: 39664382
Introduction: Chronic viral infection may lead to an immunosuppressive microenvironment, whereas the association between virus-related indicators and treatment response in hepatocellular carcinoma(HCC) patients undergoing immune checkpoint inhibitors(ICIs) therapy remains a...
4.
Li X, Guo F, Deng J, Li J, Zhang J, Fu M, et al.
Immun Inflamm Dis . 2024 Nov; 12(11):e70064. PMID: 39545659
Background: Chronic refractory wounds refer to wounds that cannot be repaired timely. Platelet-rich plasma (PRP) has significant potential in chronic wound healing therapy. The exosomes isolated from PRP were proved...
5.
Li J, Ding F, Zhang S, Jia Y, Zhang T, Wang S, et al.
BMC Cancer . 2024 Oct; 24(1):1292. PMID: 39425079
Background: Gastric cancer is a significant global malignancy with poor prognosis. Although the emergence of immune checkpoint inhibitors (ICIs) prolonged the duration of survival, resistance and progression are inevitable. We...
6.
Li J, Duan R, Traore E, Nguyen R, Davis I, Griffth W, et al.
Angew Chem Int Ed Engl . 2024 Sep; 63(49):e202407018. PMID: 39300819
Bifunctional catalase-peroxidase (KatG) features a posttranslational methionine-tyrosine-tryptophan (MYW) crosslinked cofactor crucial for its catalase function, enabling pathogens to neutralize hydrogen peroxide during infection. We discovered the presence of indole nitrogen-linked...
7.
Duan R, Li J, Liu A
Methods Enzymol . 2024 Sep; 703:147-166. PMID: 39260994
Mammalian cysteamine dioxygenase (ADO), a mononuclear non-heme Fe(II) enzyme with three histidine ligands, plays a key role in cysteamine catabolism and regulation of the N-degron signaling pathway. Despite its importance,...
8.
Li J, Duan R, Liu A
J Am Chem Soc . 2024 Jun; 146(27):18292-18297. PMID: 38941563
We investigated the metal-substituted catalytic activity of human cysteamine dioxygenase (ADO), an enzyme pivotal in regulating thiol metabolism and contributing to oxygen homeostasis. Our findings demonstrate the catalytic competence of...
9.
Zhang J, Zhang S, Xu S, Zhang X, Li J, Ji Z, et al.
Iran J Immunol . 2023 May; 20(2):240-246. PMID: 37179468
Immune Checkpoint Inhibitors (ICIs) have dramatically revolutionized the therapeutic approaches by which we treat a series of cancers accompanied by immune-related adverse events (irAEs). Herein, we reported an intrahepatic cholangiocarcinoma...
10.
Li J, Cao H, Li M, Shu L, Lin C
Proc Inst Mech Eng H . 2023 Mar; 237(4):443-450. PMID: 36927166
Calcified coronary lesions have been one of the more difficult types of lesion for interventional treatment, and angioplasty is required to break the calcification before stent implantation so that the...