Ian Collins
Overview
Explore the profile of Ian Collins including associated specialties, affiliations and a list of published articles.
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Articles
105
Citations
2773
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0
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Recent Articles
1.
Bouguenina H, Nicolaou S, Le Bihan Y, Bowling E, Calderon C, Caldwell J, et al.
iScience
. 2024 Apr;
27(5):109727.
PMID: 38646177
[This corrects the article DOI: 10.1016/j.isci.2023.107059.].
2.
Alexander M, Collins I, Abraham P, Underhill C, Harris S, Torres J, et al.
Intern Med J
. 2023 Dec;
53(12):2346-2349.
PMID: 38130050
This cost analysis, from a societal perspective, compared the cost difference of a networked teletrial model (NTTM) with four regional hubs versus conventional trial operation at a single metropolitan specialist...
3.
Liu M, Mirza A, McAndrew P, Thapaliya A, Pierrat O, Stubbs M, et al.
J Med Chem
. 2023 Jul;
66(15):10617-10627.
PMID: 37467168
High hit rates from initial ligand-observed NMR screening can make it challenging to prioritize which hits to follow up, especially in cases where there are no available crystal structures of...
4.
Bouguenina H, Scarpino A, OHanlon J, Warne J, Wang H, Wah Hak L, et al.
Chembiochem
. 2023 Jul;
24(23):e202300351.
PMID: 37418539
Small molecules inducing protein degradation are important pharmacological tools to interrogate complex biology and are rapidly translating into clinical agents. However, to fully realise the potential of these molecules, selectivity...
5.
Bouguenina H, Nicolaou S, Le Bihan Y, Bowling E, Calderon C, Caldwell J, et al.
iScience
. 2023 Jun;
26(7):107059.
PMID: 37360684
To address the limitation associated with degron based systems, we have developed iTAG, a synthetic tag based on IMiDs/CELMoDs mechanism of action that improves and addresses the limitations of both...
6.
Saint-Dizier F, Matthews T, Gregson A, Prevet H, McHardy T, Colombano G, et al.
J Med Chem
. 2023 Feb;
66(4):2622-2645.
PMID: 36749938
The existence of multiple centrosomes in some cancer cells can lead to cell death through the formation of multipolar mitotic spindles and consequent aberrant cell division. Many cancer cells rely...
7.
Antolin A, Sanfelice D, Crisp A, Villasclaras Fernandez E, Mica I, Chen Y, et al.
Nucleic Acids Res
. 2022 Oct;
51(D1):D1492-D1502.
PMID: 36268860
We describe the Chemical Probes Portal (https://www.chemicalprobes.org/), an expert review-based public resource to empower chemical probe assessment, selection and use. Chemical probes are high-quality small-molecule reagents, often inhibitors, that are...
8.
Hunter J, Campbell A, Hannaway N, Kerridge S, Luli S, Butterworth J, et al.
Biochem J
. 2022 Oct;
479(19):2063-2086.
PMID: 36240066
Previously, we discovered that deletion of c-Rel in the Eµ-Myc mouse model of lymphoma results in earlier onset of disease, a finding that contrasted with the expected function of this...
9.
Hunter J, Campbell A, Butterworth J, Sellier H, Hannaway N, Luli S, et al.
Biochem J
. 2022 Oct;
479(19):2087-2113.
PMID: 36240065
No abstract available.
10.
Sialana F, Roumeliotis T, Bouguenina H, Wah Hak L, Wang H, Caldwell J, et al.
J Proteome Res
. 2022 Jul;
21(8):1842-1856.
PMID: 35848491
Large scale proteomic profiling of cell lines can reveal molecular signatures attributed to variable genotypes or induced perturbations, enabling proteogenomic associations and elucidation of pharmacological mechanisms of action. Although isobaric...