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Ian A Marozas

Explore the profile of Ian A Marozas including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 178
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Recent Articles
1.
Azagarsamy M, Marozas I, Spaans S, Anseth K
ACS Macro Lett . 2022 Jun; 5(1):19-23. PMID: 35668597
Photodriven click reactions have emerged as versatile tools for biomaterial synthesis that can recapitulate critical spatial and temporal changes of extracellular matrix (ECM) microenvironments in vitro. In this article, we...
2.
Wojda S, Marozas I, Anseth K, Yaszemski M, Donahue S
Tissue Eng Part A . 2020 Jul; 27(3-4):246-255. PMID: 32615861
Characterizing the release profile for materials-directed local delivery of bioactive molecules and its effect on bone regeneration is an important step to improve our understanding of, and ability to optimize,...
3.
Wojda S, Marozas I, Anseth K, Yaszemski M, Donahue S
J Orthop Res . 2019 Nov; 38(3):536-544. PMID: 31709588
Neither allograft nor commercially available bone graft substitutes provide the same quality of bone healing as autograft. Incorporation of bioactive molecules like parathyroid hormone (PTH) within bone graft substitute materials...
4.
Marozas I, Anseth K, Cooper-White J
Biomaterials . 2019 Sep; 223:119430. PMID: 31493696
Cells are capable of sensing the differences in elastic and viscous properties (i.e., the 'viscoelasticity') of their tissue microenvironment and responding accordingly by changing their transcriptional activity and modifying their...
5.
Brown T, Silver J, Worrell B, Marozas I, Yavitt F, Gunay K, et al.
J Am Chem Soc . 2018 Sep; 140(37):11585-11588. PMID: 30183266
Muscle cells sense the mechanical properties of their microenvironment, and these properties can change in response to injury or disease. Hydrogels with dynamic material properties can be used to study...
6.
Newman M, Russell S, Schmitt C, Marozas I, Sheu T, Puzas J, et al.
Biomacromolecules . 2017 Dec; 19(1):71-84. PMID: 29227674
Drug delivery to bone is challenging, whereby drug distribution is commonly <1% of injected dose, despite development of several bone-targeted drug delivery systems specific to hydroxyapatite. These bone-targeted drug delivery...
7.
Hodgson S, McNelles S, Abdullahu L, Marozas I, Anseth K, Adronov A
Biomacromolecules . 2017 Oct; 18(12):4054-4059. PMID: 28968079
A common issue with hydrogel formulations is batch-to-batch irreproducibility originating from poorly defined polymer precursors. Here, we report the use of dendritic polymer end-groups to address this issue and maintain...
8.
Brown T, Marozas I, Anseth K
Adv Mater . 2017 Jan; 29(11). PMID: 28112845
Hydrogels crosslinked by allyl-sulfide-containing molecules are presented. By exposure to light in the presence of a photoinitiator and a free monofunctional thiol, photodegradation is achieved. Both the gelation and degradation...
9.
Grim J, Marozas I, Anseth K
J Control Release . 2015 Aug; 219:95-106. PMID: 26315818
Hydrogels have emerged as promising scaffolds in regenerative medicine for the delivery of biomolecules to promote healing. However, increasing evidence suggests that the context that biomolecules are presented to cells...