Danielle S W Benoit
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Explore the profile of Danielle S W Benoit including associated specialties, affiliations and a list of published articles.
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105
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Recent Articles
1.
March A, Wu H, Choe R, Benoit D
J Biomed Mater Res A
. 2025 Mar;
113(3):e37890.
PMID: 40033815
Although allografts remain the gold standard for treating critical-size bone defects, ~60% fail within 10 years of implantation. To emulate periosteum-mediated healing of live autografts, we have developed a tissue-engineered...
2.
March A, Hebner T, Choe R, Benoit D
Biomater Adv
. 2025 Jan;
169:214187.
PMID: 39827700
A common strategy for promoting bone allograft healing is the design of tissue-engineered periosteum (TEP) to orchestrate host-tissue infiltration. However, evaluating requires costly and time-consuming in vivo studies. Therefore, in...
3.
Adjei-Sowah E, Rangasami V, Loiselle A, Benoit D
ACS Appl Mater Interfaces
. 2024 Dec;
16(50):68864-68876.
PMID: 39630483
In many tissues, including musculoskeletal tissues such as tendon, systemic delivery typically results in poor targeting of free drugs. Hence, we previously developed a targeted drug delivery nanoparticle (NP) system...
4.
Dorogin J, Benz M, Moore C, Benoit D, Hettiaratchi M
Cell Mol Bioeng
. 2024 Oct;
17(4):305-312.
PMID: 39372554
Purpose: Affibodies are a class of versatile affinity proteins with a wide variety of therapeutic applications, ranging from contrast agents for imaging to cell-targeting therapeutics. We have identified several affibodies...
5.
Adjei-Sowah E, Chandrasiri I, Xiao B, Liu Y, Ackerman J, Soto C, et al.
Sci Adv
. 2024 Jun;
10(25):eadn2332.
PMID: 38896625
Satisfactory healing following acute tendon injury is marred by fibrosis. Despite the high frequency of tendon injuries and poor outcomes, there are no pharmacological therapies in use to enhance the...
6.
Hebner T, Kirkpatrick B, Fairbanks B, Bowman C, Anseth K, Benoit D
Adv Sci (Weinh)
. 2024 Apr;
11(25):e2402191.
PMID: 38582514
Michael addition between thiol- and maleimide-functionalized molecules is a long-standing approach used for bioconjugation, hydrogel crosslinking, and the functionalization of other advanced materials. While the simplicity of this chemistry enables...
7.
Xiao B, Ackun-Farmmer M, Adjei-Sowah E, Liu Y, Chandrasiri I, Benoit D
ACS Biomater Sci Eng
. 2024 Mar;
10(4):2224-2234.
PMID: 38537162
Designing targeted drug delivery systems to effectively treat bone diseases ranging from osteoporosis to nonunion bone defects remains a significant challenge. Previously, nanoparticles (NPs) self-assembled from diblock copolymers of poly(styrene--maleic...
8.
da Costa Sousa M, Vignolo S, Franca C, Mereness J, Alves Fraga M, Silva-Sousa A, et al.
Biomicrofluidics
. 2024 Mar;
18(2):021502.
PMID: 38464668
Head and neck cancers (HNCs) rank as the sixth most common cancer globally and result in over 450 000 deaths annually. Despite considerable advancements in diagnostics and treatment, the 5-year...
9.
Adjei-Sowah E, Chandrasiri I, Xiao B, Liu Y, Ackerman J, Soto C, et al.
bioRxiv
. 2023 Dec;
PMID: 38076889
Tendon regeneration following acute injury is marred by a fibrotic healing response that prevents complete functional recovery. Despite the high frequency of tendon injuries and the poor outcomes, including functional...
10.
Xiao B, Adjei-Sowah E, Benoit D
Nanomedicine
. 2023 Dec;
56:102727.
PMID: 38056586
Fracture healing is a complex interplay of molecular and cellular mechanisms lasting from days to weeks. The inflammatory phase is the first stage of fracture healing and is critical in...