I van de Rijn
Overview
Explore the profile of I van de Rijn including associated specialties, affiliations and a list of published articles.
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Articles
52
Citations
1049
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Recent Articles
1.
Campbell R, Mosimann S, van de Rijn I, Tanner M, Strynadka N
Biochemistry
. 2000 Jun;
39(23):7012-23.
PMID: 10841783
Bacterial UDP-glucose dehydrogenase (UDPGlcDH) is essential for formation of the antiphagocytic capsule that protects many virulent bacteria such as Streptococcus pyogenes andStreptococcus pneumoniae type 3 from the host's immune system....
2.
Bernish B, van de Rijn I
J Biol Chem
. 1999 Feb;
274(8):4786-93.
PMID: 9988717
Hyaluronic acid production by group A streptococci is regulated by transcriptional control. In this study, transposon mutagenesis of an unencapsulated strain yielded an encapsulated mutant. Two genes homologous to sensors...
3.
Manganelli R, van de Rijn I
Infect Immun
. 1998 Dec;
67(1):50-6.
PMID: 9864195
Streptococcus defectivus is one of the nutritionally variant streptococci, a class of viridans group streptococci first isolated from patients with endocarditis and otitis media. In previous studies, NVS-47, a clinical...
4.
Sunthankar P, Pastuszak I, Rooke A, Elbein A, van de Rijn I, Canfield W, et al.
Anal Biochem
. 1998 May;
258(2):195-201.
PMID: 9570829
Nuleotide sugar photoaffinity analogs have proven to be useful in the identification and characterization of glycosyltransferases. A radioenzymatic synthesis of [32P]5-azido-UDP-N-acetylglucosamine has been accomplished using 5-azido-UTP, [gamma-32P]ATP, porcine N-acetylgalactosamine kinase,...
5.
Campbell R, Sala R, van de Rijn I, Tanner M
J Biol Chem
. 1997 Feb;
272(6):3416-22.
PMID: 9013585
UDP-glucuronic acid is used by many pathogenic bacteria in the construction of an antiphagocytic capsule that is required for virulence. The enzyme UDP-glucose dehydrogenase catalyzes the NAD+-dependent 2-fold oxidation of...
6.
van de Rijn I, Bernish B, Crater D
Adv Exp Med Biol
. 1997 Jan;
418:965-9.
PMID: 9331811
No abstract available.
7.
Crater D, Dougherty B, van de Rijn I
J Biol Chem
. 1995 Dec;
270(48):28676-80.
PMID: 7499387
Hyaluronic acid is a high molecular weight glycosaminoglycan composed of repeating subunits of glucuronic acid and N-acetylglucosamine. It is synthesized by the group A streptococcal membrane-associated enzyme hyaluronate synthase. In...
8.
Crater D, van de Rijn I
J Biol Chem
. 1995 Aug;
270(31):18452-8.
PMID: 7629171
The has operon is composed of three genes, hasA, hasB, and hasC that encode hyaluronate synthase, UDP-glucose dehydrogenase, and presumptively UDP-glucose pyrophosphorylase, respectively. Expression of the has operon was shown...
9.
van de Rijn I, Crater D, Dougherty B
Dev Biol Stand
. 1995 Jan;
85:219-23.
PMID: 8586180
No abstract available.
10.
Dougherty B, van de Rijn I
J Biol Chem
. 1994 Jan;
269(1):169-75.
PMID: 8276791
The mechanism by which group A streptococci produce the antiphagocytic hyaluronate (hyaluronic acid) capsule is incompletely understood. Enzymes known to be essential for synthesis of this polysaccharide include the membrane-associated...