I Umeda
Overview
Explore the profile of I Umeda including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
441
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Recent Articles
1.
Wang J, Umeda I, Lin C, Chen H, Chou C, Chi C
J Gastroenterol Hepatol
. 2006 Mar;
21(2):477.
PMID: 16509881
No abstract available.
2.
Shimma N, Umeda I, Arasaki M, Murasaki C, Masubuchi K, Kohchi Y, et al.
Bioorg Med Chem
. 2000 Sep;
8(7):1697-706.
PMID: 10976516
To identify an orally available fluoropyrimidine having efficacy and safety profiles greatly improved over those of parenteral 5-fluorouracil (5-FU: 1), we designed a 5-FU prodrug that would pass intact through...
3.
Masubuchi K, Taniguchi M, Umeda I, Hattori K, Suda H, Kohchi Y, et al.
Bioorg Med Chem Lett
. 2000 Jul;
10(13):1459-62.
PMID: 10888332
A novel Candida albicans chitin synthase 1 (CaChs1) inhibitor, RO-41-0986 (1) was discovered by random screening. Systematic modification led to the identification of a highly potent CaChs1 inhibitor, RO-09-3024 (2),...
4.
Miwa M, Ura M, Nishida M, Sawada N, Ishikawa T, Mori K, et al.
Eur J Cancer
. 1998 Dec;
34(8):1274-81.
PMID: 9849491
Capecitabine (N4-pentyloxycarbonyl-5'-deoxy-5-fluorocytidine) is a novel oral fluoropyrimidine carbamate, which is converted to 5-fluorouracil (5-FU) selectively in tumours through a cascade of three enzymes. The present study investigated tissue localisation of...
5.
Ohwada J, Umeda I, Ontsuka H, Aoki Y, Shimma N
Chem Pharm Bull (Tokyo)
. 1994 Aug;
42(8):1703-5.
PMID: 7954924
A new antifungal substance, azoxybacilin (an unusual amino acid with an azoxy moiety) and its derivatives have been synthesized from Boc-L-Asp-OtBu utilizing the Moss procedure for the preparation of the...
6.
Kuriyama H, Umeda I, Kobayashi H
Can J Microbiol
. 1991 May;
37(5):397-403.
PMID: 1878818
Asexual yeast flocculation was studied using strong flocculents of Saccharomyces cerevisiae. The inhibitory effect of cations on flocculation is considered to be caused by competition between those cations and Ca2+...
7.
Nishioka R, Umeda I, Oi N, Tabata S, Uno K
J Chromatogr
. 1991 Apr;
565(1-2):237-46.
PMID: 1874870
A novel method for the determination of felodipine and its metabolites in plasma by capillary gas chromatography (GC) with electron capture detection was developed. Felodipine and its oxidized metabolite were...
8.
Miwa M, Ishikawa T, Eda H, Ryu M, Fujimoto K, Ninomiya Y, et al.
Chem Pharm Bull (Tokyo)
. 1990 Apr;
38(4):998-1003.
PMID: 2143107
N4-Trimethoxybenzoyl-5'-deoxy-5-fluorocytidine (Ro 09-1390), a new prodrug of 5'-deoxy-5-fluorouridine (5'-dFUrd), was synthesized for the purpose of finding a drug with less intestinal toxicity than the parent compound. The present study compared...
9.
Nishioka R, Harimoto T, Umeda I, Yamamoto S, Oi N
J Chromatogr
. 1990 Mar;
526(1):210-4.
PMID: 2341534
No abstract available.
10.
Ninomiya Y, Miwa M, Eda H, Sahara H, Fujimoto K, Ishida M, et al.
Jpn J Cancer Res
. 1990 Feb;
81(2):188-95.
PMID: 2139643
N4-Trimethoxybenzoyl-5'-deoxy-5-fluorocytidine (Ro 09-1390), a prodrug of the cytostatic 5'-deoxy-5-fluorouridine (5'-DFUR), was synthesized with the aim of reducing of the dose-limiting toxicity of 5'-DFUR, which is diarrhea. In mice bearing Lewis...